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Merck
CN

B9265

Anti-Mouse IgM (μ-chain specific)–Biotin antibody produced in goat

affinity isolated antibody, buffered aqueous solution

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.46
MDL number:
Conjugate:
biotin conjugate
Clone:
polyclonal
Application:
ELISA (d)
Citations:
7
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biological source

goat

Quality Level

conjugate

biotin conjugate

antibody form

affinity isolated antibody

antibody product type

secondary antibodies

clone

polyclonal

form

buffered aqueous solution

technique(s)

direct ELISA: 1:20,000

storage temp.

2-8°C

target post-translational modification

unmodified

General description

IgM is a glycoprotein antibody that regulates humoral immune responses. Mouse IgM is involved in modulating B cell memory . This antibody isotype has also been implicated in the development of autoimmune responses associated with the pathogenesis of type 1 diabetes in mice . Anti-Mouse IgM (μ-chain specific)-Biotin antibody is specific for mouse IgM when tested against mouse IgA, IgG, and IgM by ELISA.

Immunogen

Mouse IgM

Application

Anti-Mouse IgM (μ-chain specific)-Biotin antibody is suitable for use in immunocytochemistry (at 1:500 dilutions in methanol-fixed, sheep embryo sections) and direct ELISA (1:20,000).

Physical form

Solution in 0.01 M phosphate buffered saline pH 7.4, containing 1% bovine serum albumin and 15 mM sodium azide

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


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Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

常规特殊物品
低风险生物材料

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Xiangang Zou et al.
Journal of immunology (Baltimore, Md. : 1950), 170(3), 1354-1361 (2003-01-23)
Silencing individual C (constant region) lambda genes in a kappa(-/-) background reduces mature B cell levels, and L chain-deficient (lambda(-/-)kappa(-/-)) mice attain a complete block in B cell development at the stage when L chain rearrangement, resulting in surface IgM
Thea Shavlakadze et al.
Neuromuscular disorders : NMD, 15(2), 139-146 (2005-02-08)
Loss of the nerve supply to skeletal muscle results in a relentless loss of muscle mass (atrophy) over time. The ability of insulin-like growth factor-1 to reduce atrophy resulting from denervation was examined after transection of the sciatic nerve in
M Dattena et al.
Molecular reproduction and development, 73(1), 31-39 (2005-10-06)
This study was conducted to isolate, to culture, and to characterize embryonic cell lines from in vitro produced vitrified sheep blastocysts. Embryos were produced and vitrified at the expanded blastocyst stage. Ten inner cell masses arising from day 6-7 blastocysts



Global Trade Item Number

SKUGTIN
B9265-1ML04061837515019
B9265-.5ML04061837515002