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关于此项目
经验公式（希尔记法）:
C53H93N2O15Ni
化学文摘社编号:
分子量:
1057.00
MDL number:
NACRES:
NA.25
UNSPSC Code:
12352211
description
1,2-dioleoyl-sn-glycero-3-[(N-(5-amino-1-carboxypentyl)iminodiacetic acid)succinyl] (nickel salt)
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 10 mg (790404P-10mg), pkg of 1 × 25 mg (790404P-25mg), pkg of 1 × 5 mg (790404P-5mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand
shipped in
dry ice
storage temp.
−20°C
General description
1,2-二油酰基-sn-甘油基-3-[（N-（5-氨基-1-羧基戊基）亚氨基二乙酸）琥珀酰基]氮川三乙酸（NTA）（18：1 DGS-NTA（Ni））是含镍的共轭磷脂 。NTA与镍离子中存在六个配位点中的四个螯合。
Application
1,2-二油酰基-sn-甘油基-3-[（N-（5-氨基-1-羧基戊基）亚氨基二乙酸）琥珀酰基]（镍盐）（18：1 DGS-NTA（Ni））用于：
- 制备含卟啉-磷脂（PoP）偶联物的脂质体，用于蛋白质和肽的结合研究
- 制备纳米级多层囊泡（NMV），用于抗原递送研究
- 作为小单层囊泡（SUV）成分，用于制备平面脂质膜（PM）
Biochem/physiol Actions
1,2-二油酰基-sn-甘油基-3-[（N-（5-氨基-1-羧基戊基）亚氨基二乙酸）琥珀酰基]氮川三乙酸（NTA）（18：1 DGS-NTA（Ni））可用于结构生物学，尤其适合重组组氨酸标签结合蛋白。 虽然用处很大，但纳米颗粒在生物样品中存在稳定性问题。因此，NTA-脂质缀合物主要用作脂质体或纳米颗粒涂层。基于DGS-NTA（Ni）的纳米级多层囊泡（NMV）是有效的疫苗递送系统。
Packaging
5 mL透明玻璃密封安瓿（790404P-25mg）
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
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存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
No data available
flash_point_c
No data available
Kelly A Dryden et al.
Protein science : a publication of the Protein Society, 18(12), 2629-2635 (2009-10-22)
Bacterial microcompartments (BMCs) are large intracellular bodies that serve as simple organelles in many bacteria. They are proteinaceous structures composed of key enzymes encapsulated by a polyhedral protein shell. In previous studies, the organization of these large shells has been
Priyanka D Abeyrathne et al.
Methods in enzymology, 481, 25-43 (2010-10-05)
Electron crystallography is a powerful technique for the structure determination of membrane proteins as well as soluble proteins. Sample preparation for 2D membrane protein crystals is a crucial step, as proteins have to be prepared for electron microscopy at close
Anthony L Shrout et al.
Biochemistry, 42(46), 13379-13385 (2003-11-19)
Transmembrane receptors in the signaling pathways of bacterial chemotaxis systems influence cell motility by forming noncovalent complexes with the cytoplasmic signaling proteins to regulate their activity. The requirements for receptor-mediated activation of CheA, the principal kinase of the Escherichia coli
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 790404P-25MG | 04061835185061 |
| 790404P-10MG | 04061835185054 |
| 790404P-5MG | 04061835185078 |