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Merck
CN

810255P

Avanti

TopFluor胆固醇

Avanti Research - A Croda Brand

别名:

Bodipy胆固醇;Bdp-Chol

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关于此项目

经验公式(希尔记法):
C36H51BF2N2O
化学文摘社编号:
分子量:
576.61
MDL number:
NACRES:
NA.25
UNSPSC Code:
12352211
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description

23-(dipyrrometheneboron difluoride)-24-norcholesterol

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 mg (810255P-1mg), pkg of 1 × 10 mg (810255P-10mg), pkg of 1 × 5 mg (810255P-5mg)

manufacturer/tradename

Avanti Research - A Croda Brand

shipped in

dry ice

storage temp.

−20°C

General description

附着在BODIPY上的生物分子在可见光下很容易被吸收。它导致更大的荧光量子产率。它具有很高的光稳定性,并且对极性和pH的变化不太敏感。

Application

TOPFLUOR适用于:
  • 胆固醇摄取测定
  • 在活细胞实验中用于BODIPY胆固醇标记
  • 通过聚乙烯醇(PVA)辅助的脂质溶胀形成巨大的Janus脂质体

Biochem/physiol Actions

BODIPY标记的胆固醇具有与天然胆固醇相似的特性。它可充当活细胞的胆固醇标志物,并有助于运输细胞内的胆固醇。它也可能有助于指示脂质储存疾病。

Packaging

5 mL棕色玻璃螺旋盖小瓶(810255P-10mg)
5 mL棕色玻璃螺旋盖小瓶(810255P-1mg)
5 mL棕色玻璃螺旋盖小瓶(810255P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC
TopFluor is a trademark of Avanti Polar Lipids, LLC


存储类别

11 - Combustible Solids

wgk

WGK 3



历史批次信息供参考:

分析证书(COA)

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商品

Explore full-spectrum fluorophores, fluorescent lipids, and probes for imaging, membrane studies, and labeling with TopFluor™, squaraines, and more.


Frederik W Lund et al.
BMC biophysics, 5, 20-20 (2012-10-20)
Cholesterol is an important membrane component, but our knowledge about its transport in cells is sparse. Previous imaging studies using dehydroergosterol (DHE), an intrinsically fluorescent sterol from yeast, have established that vesicular and non-vesicular transport modes contribute to sterol trafficking
Maarit Hölttä-Vuori et al.
Traffic (Copenhagen, Denmark), 9(11), 1839-1849 (2008-07-24)
Analysis of sterol distribution and transport in living cells has been hampered by the lack of bright, photostable fluorescent sterol derivatives that closely resemble cholesterol. In this study, we employed atomistic simulations and experiments to characterize a cholesterol compound with
Robert M Littleton et al.
BMC complementary and alternative medicine, 12, 105-105 (2012-07-25)
Consumers are increasingly turning to plant-based complementary and alternative medicines to treat hypercholesterolemia. Many of these treatments are untested and their efficacy is unknown. This multitude of potential remedies necessitates a model system amenable to testing large numbers of organisms



全球贸易项目编号

货号GTIN
810255P-1MG04061835185634
810255P-10MG04061835185627
810255P-5MG04061835185641