登录 查看组织和合同定价。
选择尺寸
变更视图
关于此项目
经验公式（希尔记法）:
C40H79NO3
化学文摘社编号:
分子量:
622.06
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
产品名称
C22神经酰胺（d18：1/22：0）, Avanti Research™ - A Croda Brand 860501P, powder
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 10 mg (860501P-10mg), pkg of 1 × 5 mg (860501P-5mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 860501P
lipid type
sphingolipids
shipped in
dry ice
storage temp.
−20°C
SMILES string
OC[C@]([H])(NC(CCCCCCCCCCCCCCCCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCCC
InChI
1S/C40H79NO3/c1-3-5-7-9-11-13-15-17-18-19-20-21-22-24-26-28-30-32-34-36-40(44)41-38(37-42)39(43)35-33-31-29-27-25-23-16-14-12-10-8-6-4-2/h33,35,38-39,42-43H,3-32,34,36-37H2,1-2H3,(H,41,44)/b35-33+/t38-,39+/m0/s1
InChI key
KEPQASGDXIEOIL-GLQCRSEXSA-N
General description
C22神经酰胺(d18:1/22:0)或N-山嵛酰-D-赤型-鞘氨醇是一种人工合成的、由鞘氨醇和山嵛酸组成的神经酰胺。
Application
C22神经酰胺(d18:1/22:0)已用于：
- 作为标准品，用于通过高效液相色谱/串联质谱(LC/MS2)技术测定肌肉组织样品中的神经酰胺浓度
- 作为鞘脂代谢物的定量分析标准品
- 研究其对线粒体-胞浆应激反应(MCSR)诱发的影响
Biochem/physiol Actions
神经酰胺在细胞分化、增殖和凋亡调节中起重要作用。还能调节应激和炎症反应。
Packaging
5 mL棕色玻璃螺旋盖样品瓶（860501P-10mg）
5 mL棕色玻璃螺旋盖样品瓶（860501P-5mg）
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
Hyun-Eui Kim et al.
Cell, 166(6), 1539-1552 (2016-09-10)
Defects in mitochondrial metabolism have been increasingly linked with age-onset protein-misfolding diseases such as Alzheimer's, Parkinson's, and Huntington's. In response to protein-folding stress, compartment-specific unfolded protein responses (UPRs) within the ER, mitochondria, and cytosol work in parallel to ensure cellular
Donato A Rivas et al.
Journal of applied physiology (Bethesda, Md. : 1985), 113(11), 1727-1736 (2012-10-09)
One of the most fundamental adaptive physiological events is the response of skeletal muscle to high-intensity resistance exercise, resulting in increased protein synthesis and ultimately larger muscle mass. However, muscle growth in response to contraction is attenuated in older humans.
Ebru Afşar et al.
Redox biology, 30, 101430-101430 (2020-01-25)
We aimed to determine sphingolipid levels and examine apoptotic pathways in human retinal pigment epithelial cells (ARPE-19) undergoing endoplasmic reticulum (ER) stress. Cells were treated with tunicamycin (TM) to induce ER stress and tauroursodeoxycholic acid (TUDCA), an ER stress inhibitor
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 860501P-10MG | 04061835317424 |
| 860501P-5MG | 04061835317431 |