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关于此项目
经验公式（希尔记法）:
C30H59NO3
化学文摘社编号:
分子量:
481.79
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 10 mg (860512P-10mg), pkg of 1 × 25 mg (860512P-25mg), pkg of 1 × 5 mg (860512P-5mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand
lipid type
sphingolipids
shipped in
dry ice
storage temp.
−20°C
SMILES string
OC[C@]([H])(NC(CCCCCCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCCC
InChI
1S/C30H59NO3/c1-3-5-7-9-11-13-14-15-16-18-19-21-23-25-29(33)28(27-32)31-30(34)26-24-22-20-17-12-10-8-6-4-2/h23,25,28-29,32-33H,3-22,24,26-27H2,1-2H3,(H,31,34)/b25-23+/t28-,29+/m0/s1
InChI key
HXFPPRPLRSPNIB-VARSQMIESA-N
General description
C12神经酰胺（d18：1/12：0）是一种含有鞘氨醇和十二烷酸的合成神经酰胺。
Application
C12神经酰胺（d18:1/12:0）或N-月桂酰-D-赤型-鞘氨醇已用于：
- 作为脂质标准品，用于优化液相色谱-质谱（LC-MS）法条件
- 作为U87MG（人胶质瘤细胞系）中脂质提取的内标
- 作为液相色谱-质谱（LC-MS）法测定大鼠组织中神经酰胺含量的内标
Biochem/physiol Actions
神经酰胺是鞘脂的信号传导，与调节应激反应和炎症有关。它还调节细胞生长停滞、分化和凋亡。
Packaging
5 mL棕色玻璃螺旋盖小瓶（860512P-10mg）
5 mL棕色玻璃螺旋盖小瓶（860512P-25mg）
5 mL棕色玻璃螺旋盖小瓶（860512P-5mg）
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
wgk
WGK 3
Gergely Karsai et al.
The Journal of biological chemistry, 295(7), 1889-1897 (2019-12-22)
Sphingolipids (SLs) are structurally diverse lipids that are defined by the presence of a long-chain base (LCB) backbone. Typically, LCBs contain a single Δ4E double bond (DB) (mostly d18:1), whereas the dienic LCB sphingadienine (d18:2) contains a second DB at
Mónica Narváez-Rivas et al.
Journal of chromatography. A, 1440, 123-134 (2016-03-02)
The goal of untargeted lipidomics is to have high throughput, yet comprehensive and unambiguous identification and quantification of lipids. Novel stationary phases in LC separation and new mass spectrometric instruments capable of high mass resolving power and faster scanning rate
Sonia Hernández-Tiedra et al.
Autophagy, 12(11), 2213-2229 (2016-11-02)
Autophagy is considered primarily a cell survival process, although it can also lead to cell death. However, the factors that dictate the shift between these 2 opposite outcomes remain largely unknown. In this work, we used Δ9-tetrahydrocannabinol (THC, the main
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 860512P-25MG | 04061835317516 |
| 860512P-10MG | 04061835317509 |
| 860512P-5MG | 04061835317523 |