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关于此项目
经验公式（希尔记法）:
C41H83N2O6P
化学文摘社编号:
分子量:
731.08
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 10 mg (860586P-10mg), pkg of 1 × 5 mg (860586P-5mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand
lipid type
sphingolipids
shipped in
dry ice
storage temp.
−20°C
SMILES string
[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCCCCCCCCCCCC)=O)COP([O-])(OCC[N+](C)(C)C)=O
InChI
1S/C41H83N2O6P/c1-6-8-10-12-14-16-18-20-21-23-25-27-29-31-33-35-41(45)42-39(38-49-50(46,47)48-37-36-43(3,4)5)40(44)34-32-30-28-26-24-22-19-17-15-13-11-9-7-2/h32,34,39-40,44H,6-31,33,35-38H2,1-5H3,(H-,42,45,46,47)/b34-32+/t39-,40+/m0/s1
InChI key
LKQLRGMMMAHREN-YJFXYUILSA-N
Application
N-硬脂酰-D-赤型-鞘氨醇磷酸胆碱(18:0 SM (d18:1/18:0))已用于：
- 作为脂质体组分测定ostreolysin A(OlyA)结合，用于研究磷脂酰胆碱(PC)对鞘磷脂(SM)/胆固醇相互作用的影响
- 作为鞘脂代谢物定量分析的标准品
- 作为液相色谱-串联质谱(LC/MS/MS)法对表皮脂质进行绝对定量的标准品
Packaging
5 mL棕色玻璃螺旋盖样品瓶（860586P-10mg）
5 mL棕色玻璃螺旋盖样品瓶（860586P-5mg）
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
Ebru Afşar et al.
Redox biology, 30, 101430-101430 (2020-01-25)
We aimed to determine sphingolipid levels and examine apoptotic pathways in human retinal pigment epithelial cells (ARPE-19) undergoing endoplasmic reticulum (ER) stress. Cells were treated with tunicamycin (TM) to induce ER stress and tauroursodeoxycholic acid (TUDCA), an ER stress inhibitor
Zhixing Wang et al.
The Journal of investigative dermatology, 133(3), 668-676 (2012-10-26)
The stratum corneum is composed of protein-enriched corneocytes embedded in an intercellular matrix of nonpolar lipids organized as lamellar layers and giving rise to epidermal permeability barrier (EPB). EPB defects have an important role in the pathophysiology of skin diseases
Delphine Milhas et al.
FEBS letters, 584(9), 1887-1894 (2009-10-28)
The plasma membrane (PM) is a major resource for production of bioactive lipids and contains a large proportion of the cellular sphingomyelin (SM) content. Consequently, the regulation of SM levels at the PM by enzymes such as sphingomyelinase (SMase) and
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 860586P-10MG | 04061835318346 |
| 860586P-5MG | 04061835318353 |