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关于此项目
经验公式（希尔记法）:
C34H66O4
化学文摘社编号:
分子量:
538.89
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
产品名称
5-PAHSA, 5-(palmitoyloxy)octadecanoic acid, chloroform
assay
>99% (TLC)
form
liquid
packaging
pkg of 1 × 1 mL (900410C-1mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 900410C
concentration
1 mg/mL (900410C-1mg)
lipid type
neutral glycerides
neutral lipids
shipped in
dry ice
storage temp.
−20°C
SMILES string
CCCCCCCCCCCCCC(OC(CCCCCCCCCCCCCCC)=O)CCCC(O)=O
InChI key
QBGKCWKQYJQHJX-UHFFFAOYSA-N
General description
Palmitic acid and hydroxystearic acid (PAHSA) containing (O-acyl)-hydroxy fatty acids are being found in tissues and serum extracts of mouse and human.
Application
5-PAHSA or 5-(palmitoyloxy)octadecanoic acid might be used as (O-acyl)-hydroxy fatty acids (OAHFAs) standard to determine ester position in isomeric OAHFAs by ion trap mass spectrometry. It is also suitable for use as a standard for the quantification of fatty acid esters of hydroxy fatty acids (FAHFAs) by liquid chromatography–mass spectrometry (LC-MS).
Biochem/physiol Actions
Palmitic acid and hydroxystearic acid (PAHSA) levels correlate highly with insulin sensitivity and are reduced in adipose tissue and serum of insulin-resistant humans. In adipocytes, PAHSAs signal through G-protein-coupled receptor 120 (GPR120) to enhance insulin-stimulated glucose uptake. PAHSAs are fatty acid esters of hydroxy fatty acids (FAHFAs), which are endogenous lipids with the potential to treat diabetes and inflammation.
Packaging
5 mL Clear Glass Sealed Ampule (900410C-1mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
signalword
Danger
Hazard Classifications
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
target_organs
Central nervous system, Liver,Kidney
wgk
WGK 3
存储类别
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
flash_point_f
does not flash
flash_point_c
does not flash
法规信息
易制毒化学品（2类）
危险化学品
此项目有
David L Marshall et al.
Rapid communications in mass spectrometry : RCM, 30(21), 2351-2359 (2016-08-16)
(O-acyl)-hydroxy fatty acids (OAHFAs) are a recently discovered class of endogenous lipids, generating significant interest for their correlation with enhanced glucose tolerance. Structural variants that differ in the position of the ester linkage have been described, including the ω-OAHFA sub-class
Thu Huong Pham et al.
Molecules (Basel, Switzerland), 24(2) (2019-01-13)
Fatty acid esters of hydroxy fatty acids (FAHFA), diglycerides (DG) and monoacetyldiglycerides (MAcDG) are gaining interest as functional lipids in pharmaceuticals and functional food formulations for managing and treating metabolic or inflammatory diseases. Herein, we investigated whether the antler and/or
Yan-Mei Wang et al.
Biochemical and biophysical research communications, 506(1), 153-160 (2018-10-21)
Browning of white adipose tissue is a novel mechanism to counteract obesity in view of its thermogenic activity. Activation of G-protein-coupled receptor 120 (GPR120) can promote the browning of white fat. 9-PAHSA, an endogenous mammalian lipid, which is acting as
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 900410C-1MG | 04061838170224 |