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Merck
CN

A1270000

精氨酸

European Pharmacopoeia (EP) Reference Standard

别名:

L-精氨酸, (S)-2-氨基-5-胍基戊酸

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关于此项目

线性分子式:
H2NC(=NH)NH(CH2)3CH(NH2)CO2H
化学文摘社编号:
分子量:
174.20
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
1725413
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grade

pharmaceutical primary standard

API family

arginine

manufacturer/tradename

EDQM

mp

222 °C (dec.) (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

N[C@@H](CCCNC(N)=N)C(O)=O

InChI

1S/C6H14N4O2/c7-4(5(11)12)2-1-3-10-6(8)9/h4H,1-3,7H2,(H,11,12)(H4,8,9,10)/t4-/m0/s1

InChI key

ODKSFYDXXFIFQN-BYPYZUCNSA-N

General description

本品按现行药典规定交付。该产品的所有支持信息,包括SDS和任何产品信息宣传页均由药典发行机构制定并发布。如需更多信息和支持,请见现行药典的网站。

Application

精氨酸EP参考标准品的预期用途是欧洲药典规定的实验室测试。

Biochem/physiol Actions

一氧化氮合成酶的底物,可转化为瓜氨酸和一氧化氮 (NO)。通过与一氧化氮相关的机理诱导胰岛素释放。

Packaging

本品按照现行药典要求提供。有关当前单位数量,请见EDQM 参考目录

Other Notes

可能适用相应的销售限制。


存储类别

13 - Non Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Jurgen R Piet et al.
The Journal of infectious diseases, 209(11), 1781-1791 (2013-12-18)
Streptococcus pneumoniae (pneumococcus) is a major human pathogen causing pneumonia, sepsis and bacterial meningitis. Using a clinical phenotype based approach with bacterial whole-genome sequencing we identified pneumococcal arginine biosynthesis genes to be associated with outcome in patients with pneumococcal meningitis.
Phyllis S Y Chong et al.
Cancer research, 74(11), 3043-3053 (2014-04-02)
PRL-3, an oncogenic dual-specificity phosphatase, is overexpressed in 50% of acute myelogenous leukemia (AML) and associated with poor survival. We found that stable expression of PRL-3 confers cytokine independence and growth advantage of AML cells. However, how PRL-3 mediates these
Lindsay D Plank et al.
Hepatology (Baltimore, Md.), 61(2), 639-647 (2014-09-13)
Preliminary work suggested that perioperative immunonutrition (IMN) enriched in n-3 fatty acids, arginine, and nucleotides may improve preoperative nutritional status, enhance postoperative recovery, and reduce postoperative infectious complications in patients undergoing liver transplantation (LT). The current study examined these outcomes



全球贸易项目编号

货号GTIN
A127000004061833799239