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K2000000

酮洛芬

Name: 酮洛芬
Brand: SIAL

European Pharmacopoeia (EP) Reference Standard

别名:

2-(3-苯甲酰苯基)丙酸

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关于此项目

经验公式（希尔记法）:

C₁₆H₁₄O₃

化学文摘社编号:

22071-15-4

分子量:

254.28

NACRES:

NA.24

PubChem Substance ID:

329817130

UNSPSC Code:

41116107

MDL number:

MFCD00055790

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属性

grade

pharmaceutical primary standard

API family

ketoprofen

manufacturer/tradename

EDQM

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

CC(C(O)=O)c1cccc(c1)C(=O)c2ccccc2

InChI

1S/C16H14O3/c1-11(16(18)19)13-8-5-9-14(10-13)15(17)12-6-3-2-4-7-12/h2-11H,1H3,(H,18,19)

InChI key

DKYWVDODHFEZIM-UHFFFAOYSA-N

Gene Information

human ... PTGS1(5742), PTGS2(5743)

说明

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Ketoprofen EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Biochem/physiol Actions

非甾体类抗炎化合物，具有COX-1选择性。

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

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pictograms

GHS06,GHS09

signalword

Danger

hcodes

H301,H315,H319,H400

pcodes

P264 - P273 - P280 - P301 + P310 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Acute 1 - Eye Irrit. 2 - Skin Irrit. 2

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Ketoprofen impairs immunosuppression induced by severe sepsis and reveals an important role for prostaglandin E2.

Ariane Rennó Brogliato et al.

Shock (Augusta, Ga.), 38(6), 620-629 (2012-11-13)

The mechanism of immunosuppression induced by severe sepsis is not fully understood. The production of prostaglandin E2 (PGE2) during sepsis is well known, but its role in long-term consequences of sepsis has not been explored. The current study evaluates the

The effect of administering ketoprofen on the physiology and behavior of dairy cows following surgery to correct a left displaced abomasum.

Nathalie C Newby et al.

Journal of dairy science, 96(3), 1511-1520 (2013-01-22)

Surgical correction of left displaced abomasum (LDA) is common in lactating dairy cattle. Despite the growing acceptance that abdominal surgery is painful, few cows are administered analgesia following LDA surgery. The objective of this research was to examine the effect

Continuous-flow encapsulation of ketoprofen in copolymer microbeads via co-axial microfluidic device: influence of operating and material parameters on drug carrier properties.

Ikram Ullah Khan et al.

International journal of pharmaceutics, 441(1-2), 809-817 (2012-12-26)

Microchannels based microfluidic systems are able to obtain monodispersed microparticles but are limited by cost, time and channel clogging. We succeeded in on the fly encapsulation of high ketoprofen contents in acrylate-based copolymer microbeads by environment friendly UV induced free

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货号	GTIN
K2000000	04061833812006