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Merck
CN

N0300000

新霉胺

European Pharmacopoeia (EP) Reference Standard

别名:

2-Deoxy-4-O-(2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl)-D-streptamine

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关于此项目

经验公式(希尔记法):
C12H26N4O6
化学文摘社编号:
分子量:
322.36
UNSPSC Code:
41116107
NACRES:
NA.24
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grade

pharmaceutical primary standard

API family

neomycin

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

shipped in

wet ice

storage temp.

−20°C

SMILES string

N[C@H]1[C@H](O[C@@H]([C@H]([C@@H]1O)O)CN)O[C@H]2[C@@H]([C@H]([C@@H](C[C@@H]2N)N)O)O

InChI

1S/C12H26N4O6/c13-2-5-8(18)9(19)6(16)12(21-5)22-11-4(15)1-3(14)7(17)10(11)20/h3-12,17-20H,1-2,13-16H2/t3-,4+,5-,6-,7+,8-,9-,10-,11-,12-/m1/s1

InChI key

SYJXFKPQNSDJLI-HKEUSBCWSA-N

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets, has been developed and issued under the Authority of the issuing Pharmacopoeia.

For further information and support please go to the website of the issuing Pharmacopoeia.

Application

This European Pharmacopoeia reference standard is intended for use only as specifically prescribed in the European Pharmacopoeia. Their suitability for any other use is not guaranteed and is the sole responsibility of the user. This standard is not intended for human or animal use.
Established for the preparation of reference solutions (d) in the testing of related substances in framycetin sulfate and neomycin sulfate using liquid chromatography (General text 2.2.29), according to the monographs 0180 and 0197 of European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.


pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

涉药品监管产品

此项目有



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Tony Le Gall et al.
Bioconjugate chemistry, 20(11), 2032-2046 (2009-10-24)
With the view to develop novel bioinspired nonviral vectors for gene delivery, we synthesized a series of cationic lipids with a neamine headgroup, which incorporates rings I and II of the natural antibiotic aminoglycoside neomycin B. Indeed, we reasoned that
Li-Juan Pang et al.
Organic & biomolecular chemistry, 7(20), 4252-4266 (2009-10-02)
Neamine is normally found as a core structure of aminoglycoside antibiotics. In order to understand the relationship between the antibiotic activity and the configurations of the functional groups of neamine, a series of novel neamine analogues with functional group manipulations
Benedikt Huttner et al.
The Journal of antimicrobial chemotherapy, 68(10), 2375-2382 (2013-05-31)
Extended-spectrum β-lactamase-producing Enterobacteriaceae (ESBL-E) are an increasingly frequent cause of infections in the community and the healthcare setting. In this study, we aimed to investigate whether intestinal carriage of ESBL-E can be eradicated. We conducted a double-blind, randomized, placebo-controlled, single-centre



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货号GTIN
N030000004061834092872