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PHR1108

L-组氨酸

Name: <SC>L</SC>-组氨酸
Brand: SIAL

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

(S)-2-氨基-3-(4-咪唑基)丙酸, NSC 137773

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关于此项目

经验公式（希尔记法）:

C₆H₉N₃O₂

化学文摘社编号:

71-00-1

分子量:

155.15

NACRES:

NA.24

PubChem Substance ID:

329823130

eCl@ss:

32160406

UNSPSC Code:

41116107

EC Number:

200-745-3

MDL number:

MFCD00064315

Beilstein/REAXYS Number:

84088

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属性

Quality Level

300

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to Ph. Eur. H0750000, traceable to USP 1308505

API family

histidine

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

mp

282 °C (dec.) (lit.)

application(s)

cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care
pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

SMILES string

N[C@@H](Cc1c[nH]cn1)C(O)=O

InChI

1S/C6H9N3O2/c7-5(6(10)11)1-4-2-8-3-9-4/h2-3,5H,1,7H2,(H,8,9)(H,10,11)/t5-/m0/s1

InChI key

HNDVDQJCIGZPNO-YFKPBYRVSA-N

说明

General description

用于质量控制的制药二级标准品，为制药实验室和制造商制备内部工作标准品提供了一种方便、高性价比的替代方案。L-组氨酸是一种必需氨基酸，广泛存在于酶的活性部位。它可与金属离子结合，并可能有助于铜的运输。它还在蛋白质结合位点上对血红素基团、大分子和磷酸基团的结合起着重要作用。

Application

这些二级标准品是合格的认证标准物质（CRM）。它们适用于多种分析应用，包括但不限于药物释放测试、药物的定性和定量分析方法开发、食品和饮料质量控制检测以及其他校准需求。

Biochem/physiol Actions

组胺的前体,经组氨酸脱羧酶作用可生成组胺。

Analysis Note

These secondary standards offer multi-traceability to the USP and EP (PhEur) primary standards, where they are available.

Other Notes

该认证参考物质（CRM）根据 ISO 17034 和 ISO/IEC 17025 进行生产和认证。所有关于客户关系管理的信息都可以在分析证书上找到。

在我们的NMR在线平台ChemisTwin®上可以找到本品对应的数字化标准物质。您可使用ChemisTwin®上的数字等效品鉴定您的样品并进行定量分析（使用数字化外标）。可查看该物质的NMR谱图，只需点击几次鼠标，就能进行在线样品比对。欢迎点击了解更多，开启免费试用之旅。

要查看该材料的分析证书示例，请在下面的栏位中输入LRAA7159。这只是一个示例证书，可能不是您收到的批次。

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存储类别

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

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Large-scale functional expression of WT and truncated human adenosine A2A receptor in Pichia pastoris bioreactor cultures.

Shweta Singh et al.

Microbial cell factories, 7, 28-28 (2008-10-14)

The large-scale production of G-protein coupled receptors (GPCRs) for functional and structural studies remains a challenge. Recent successes have been made in the expression of a range of GPCRs using Pichia pastoris as an expression host. P. pastoris has a

Subangstrom resolution X-ray structure details aquaporin-water interactions.

Urszula Kosinska Eriksson et al.

Science (New York, N.Y.), 340(6138), 1346-1349 (2013-06-15)

Aquaporins are membrane channels that facilitate the flow of water across biological membranes. Two conserved regions are central for selective function: the dual asparagine-proline-alanine (NPA) aquaporin signature motif and the aromatic and arginine selectivity filter (SF). Here, we present the

HNH proteins are a widespread component of phage DNA packaging machines.

Smriti Kala et al.

Proceedings of the National Academy of Sciences of the United States of America, 111(16), 6022-6027 (2014-04-09)

The genome packaging reactions of tailed bacteriophages and herpes viruses require the activity of a terminase enzyme, which is comprised of large and small subunits. Phage genomes are replicated as linear concatemers composed of multiple copies of the genome joined

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全球贸易项目编号

货号	GTIN
PHR1108-1G	04061835233052