PHR1149
对乙酰氨基酚相关化合物J
Pharmaceutical Secondary Standard; Certified Reference Material
别名:
4′-氯乙酰苯胺, 4-氯乙酰苯胺, N-(4-氯苯基)乙酰胺, NSC 40563, NSC 444
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关于此项目
线性分子式:
CH3CONHC6H4Cl
化学文摘社编号:
分子量:
169.61
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
208-707-8
Beilstein/REAXYS Number:
509638
MDL number:
Quality Level
grade
certified reference material, pharmaceutical secondary standard
agency
traceable to Ph. Eur. Y0001945, traceable to USP 1003100
API family
paracetamol, acetaminophen
CofA
current certificate can be downloaded
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
mp
176-178 °C (lit.)
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-30°C
SMILES string
CC(=O)Nc1ccc(Cl)cc1
InChI
1S/C8H8ClNO/c1-6(11)10-8-4-2-7(9)3-5-8/h2-5H,1H3,(H,10,11)
InChI key
GGUOCFNAWIODMF-UHFFFAOYSA-N
General description
该认证标准物质（CRM）根据ISO 17034和ISO/IEC 17025生产和认证。有关本CRM用途的所有信息参见分析证书。
用于质量控制的药物二级标准品，为制药实验室和制造商制备内部工作标准提供了一种方便、高性价比的替代方案。
它是广泛使用的退烧及镇痛药对乙酰氨基酚（也称扑热息痛）的杂质。
用于质量控制的药物二级标准品，为制药实验室和制造商制备内部工作标准提供了一种方便、高性价比的替代方案。
它是广泛使用的退烧及镇痛药对乙酰氨基酚（也称扑热息痛）的杂质。
Application
该药物二级标准品也可用于以下应用：
- 通过高效液相色谱（HPLC）分离和评估市售对乙酰氨基酚片中的对乙酰氨基酚及其工艺杂质
- 开发和确认基于HPLC的稳定性指示方法用于测定非处方糖浆制剂中的对乙酰氨基酚、马来酸氯苯吡胺及其可能的分解产物
- 采用四种基于化学计量的分光光度法检测和定量测定对乙酰氨基酚、盐酸去氧肾上腺素和对乙酰氨基酚杂质
- 采用离子对反相液相色谱结合紫外检测分析对乙酰氨基酚、半水磷酸可待因和吡托非农盐酸盐的复方栓剂中的杂质
- 开发薄层色谱结合密度测定的方法用于分离商业剂型中的对乙酰氨基酚及其相关杂质
Analysis Note
These secondary standards offer multi-traceability to the USP and EP (PhEur) primary standards, where they are available.
Other Notes
分析物的数值在批次间变化很大。
在我们的NMR在线平台ChemisTwin®上可以找到本品对应的数字化标准物质。您可使用ChemisTwin®上的数字等效品鉴定您的样品并进行定量分析（使用数字化外标）。可查看该物质的NMR谱图，只需点击几次鼠标，就能进行在线样品比对。欢迎点击了解更多，开启免费试用之旅。
想要查看本品的检验报告示例，请在下框中输入LRAC0397。这只是一个示例证书，可能与您收到的批次不符。
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signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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全球贸易项目编号
| 货号 | GTIN |
|---|---|
| PHR1149-1G | 04061835564521 |