Quality Level
grade
certified reference material, pharmaceutical secondary standard
agency
traceable to USP 1626001
API family
sulfadimethoxine
CofA
current certificate can be downloaded
packaging
pkg of 500 mg
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-30°C
SMILES string
COc1cc(NS(=O)(=O)c2ccc(N)cc2)nc(OC)n1
InChI
1S/C12H14N4O4S/c1-19-11-7-10(14-12(15-11)20-2)16-21(17,18)9-5-3-8(13)4-6-9/h3-7H,13H2,1-2H3,(H,14,15,16)
InChI key
ZZORFUFYDOWNEF-UHFFFAOYSA-N
General description
Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Sulfadimethoxine is an long acting sulfonamide antibiotic, commonly used against a broad spectrum of bacterial infections in animals. Its mode of action involves the inhibition of folic acid synthesis in prokaryotes. It is also widely used in veterinary medication to treat coccidiosis in cats and dogs.
Application
Sulfadimethoxine may be used as a pharmaceutical reference standard for the quantification of the analyte in veterinary formulations using liquid chromatography technique.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Analysis Note
These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.
Other Notes
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAA2825 in the slot below. This is an example certificate only and may not be the lot that you receive.
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signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
存储类别
11 - Combustible Solids
wgk
WGK 3
商品
LC-MS/MS-based determination of 19 sulfonamides, 13 quinolones, and 3 tetracycline drug residues in pork meat samples using Supel™ Swift HLB for extraction.
Small Animal Clinical Pharmacology (2011)
Simultaneous determination of sulfamethoxypyridazine, sulfamethoxazole, sulfadimethoxine and their associated compounds by liquid chromatography.
Nevado JJ, et al.
Analytica Chimica Acta, 442(2), 241-248 (2001)
Minjoo Kim et al.
PloS one, 10(3), e0119519-e0119519 (2015-03-18)
Existing data on the association between being overweight and cardiovascular morbidity and mortality risk in adults are inconsistent. We prospectively and longitudinally investigated the effects of weight on arterial stiffness and plasma metabolites in middle-aged subjects (aged 40-55 years). A
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| PHR1448-500MG | 04061834416708 |
