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Merck
CN

Y0001406

氨基葡萄糖 盐酸盐

European Pharmacopoeia (EP) Reference Standard

别名:

D- (+)-氨基葡萄糖 盐酸盐, 2-氨基-2-脱氧-D-葡萄糖 盐酸盐, 壳糖胺 盐酸盐

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关于此项目

经验公式(希尔记法):
C6H13NO5 · HCl
化学文摘社编号:
分子量:
215.63
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
Beilstein/REAXYS Number:
4157370
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grade

pharmaceutical primary standard

agency

EP Reference Standard

API family

glucosamine

manufacturer/tradename

EDQM

mp

190-194 °C (dec.) (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

Cl.N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O

InChI

1S/C6H13NO5.ClH/c7-3-5(10)4(9)2(1-8)12-6(3)11;/h2-6,8-11H,1,7H2;1H/t2-,3-,4-,5-,6?;/m1./s1

InChI key

QKPLRMLTKYXDST-NSEZLWDYSA-N

General description

本品按现行药典规定交付。所有为支持本产品而提供的信息,包括SDS和任何产品信息单均由药典颁发机构制定并发布。如需进一步信息和支持,请访问现行药典网站。

Application

盐酸氨基葡萄糖EP参考标准品的预期用途是欧洲药典规定的实验室测试。

Biochem/physiol Actions

葡萄糖胺是一种氨基糖,是己糖胺生物合成途径的前体,可导致形成UDP-N-乙酰葡糖胺(UDP-GlcNAc),然后将其用于制备糖胺聚糖、蛋白多糖和糖脂。 D-(+)-葡萄糖胺抑制念珠菌酵母菌株与细菌菌株唾液链球菌的共聚集。

Packaging

本品按照现行药典要求提供。有关当前单位数量,请见EDQM 参考目录

Other Notes

可能适用相应的销售限制。


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存储类别

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Oshra Betzer et al.
ACS nano, 8(9), 9274-9285 (2014-08-19)
A critical problem in the development and implementation of stem cell-based therapy is the lack of reliable, noninvasive means to image and trace the cells post-transplantation and evaluate their biodistribution, final fate, and functionality. In this study, we developed a
Ji-Sun Hwang et al.
Metabolism: clinical and experimental, 64(3), 368-379 (2014-12-18)
This study investigated the potential of glucosamine (GlcN) to affect body weight gain and insulin sensitivity in mice normal and at risk for developing diabetes. Male C57BL/6J mice were fed either chow diet (CD) or a high fat diet (HFD)
Viktor Chesnokov et al.
Cancer cell international, 14, 45-45 (2014-06-17)
We have reported that the glucosamine suppressed the proliferation of the human prostate carcinoma cell line DU145 through inhibition of STAT3 signaling. DU145 cells autonomously express IL-6 and the IL-6/STAT3 signaling is activated. IL-6 receptor subunits are subject to N-glycosylation



全球贸易项目编号

货号GTIN
Y000140604061833797747