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A9013

1,5-双（4-烯丙基二甲基氨苯基）戊-3-酮二溴

Name: 1,5-双（4-烯丙基二甲基氨苯基）戊-3-酮二溴
Brand: SIGMA

≥97% (HPLC), acetylcholinesterase inhibitor, powder

别名:

BW 284c51

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关于此项目

线性分子式:

C₂₇H₃₈N₂OBr₂

化学文摘社编号:

402-40-4

分子量:

566.41

UNSPSC Code:

12352200

PubChem Substance ID:

24278243

NACRES:

NA.77

MDL number:

MFCD00063485

Assay:

≥97% (HPLC)

Form:

powder

Quality level:

200

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属性

产品名称

1,5-双（4-烯丙基二甲基氨苯基）戊-3-酮二溴,

assay

≥97% (HPLC)

Quality Level

200

form

powder

solubility

water: 19.60-20.40 mg/mL, clear, colorless

storage temp.

room temp

SMILES string

Br.C[N](C)(CC=C)c1ccc(CCC(=O)CCc2ccc(cc2)[N](C)(C)CC=C)cc1

InChI

1S/C27H38N2O.BrH/c1-7-21-28(3,4)25-15-9-23(10-16-25)13-19-27(30)20-14-24-11-17-26(18-12-24)29(5,6)22-8-2;/h7-12,15-18H,1-2,13-14,19-22H2,3-6H3;1H

InChI key

XBXRQUYORADPMX-UHFFFAOYSA-N

Gene Information

human ... ACHE(43)

说明

Biochem/physiol Actions

Selective acetylcholinesterase inhibitor.

Features and Benefits

This compound is featured on the Acetylcholine Synthesis and Metabolism page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

pictograms

GHS06

signalword

Danger

hcodes

H300 + H310 + H330

pcodes

P260 - P262 - P264 - P280 - P302 + P352 + P310 - P304 + P340 + P310

Hazard Classifications

Acute Tox. 2 Oral

存储类别

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

历史批次信息供参考:

分析证书(COA)

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Modulated growth of nanoparticles. Application for sensing nerve gases.

Ana Virel et al.

Analytical chemistry, 81(1), 268-272 (2008-12-04)

Hydrolysis of acetylthiocholine mediated by acetylcholine esterase yields the thiol-bearing compound thiocholine. At trace concentrations, thiocholine modulates the growth of Au-Ag nanoparticles on seeding gold nanoparticles in the presence of ascorbic acid. Inhibition of the enzyme by 1,5-bis(4-allyldimethylammoniumphenyl)pentan-3-one dibromide (BW284c51)

Baculovirus expression of BmAChE3, a cDNA encoding an acetylcholinesterase of Boophilus microplus (Acari: Ixodidae).

Kevin B Temeyer et al.

Journal of medical entomology, 43(4), 707-712 (2006-08-09)

The complete cDNA sequence encoding a Boophilus microplus (Canestrini) (Acari: Ixodidae) acetylcholinesterase (AChE3) was expressed in the baculovirus system. The recombinant AChE3 protein (rBmAChE3) was secreted as a soluble form into the cell culture medium and was identified as a

Retardation of neuritic outgrowth and cytoskeletal changes accompany acetylcholinesterase inhibitor treatment in cultured rat dorsal root ganglion neurons.

J L Dupree et al.

Journal of neuroscience research, 39(5), 567-575 (1994-12-01)

Over the past two decades acetylcholinesterase (AChE) has been shown to be present in numerous non-cholinergic and non-cholinoceptive tissues. Interestingly, transient expression of AChE in developing nervous tissue corresponds temporally with neuronal migration and neuritic outgrowth. This observation has led

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货号	GTIN
A9013-25MG	04061833401170
A9013-100MG	04061833401163
A9013-250MG	04061832945316