biological source
mouse
Quality Level
conjugate
unconjugated
antibody form
ascites fluid
antibody product type
primary antibodies
clone
BU-33, monoclonal
species reactivity
wide range
technique(s)
immunocytochemistry: suitable, immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:1000 using sections of intestine from mouse or rat treated in vivo with BrdU
isotype
IgG1
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
General description
5′-溴-2-脱氧尿苷(BrdU)是一种可被皮肤吸收或吸入的致癌物质。BrdU溶液对光敏感。单克隆抗BrdU(免疫组织学等级)(小鼠IgG1同种型)分离自BU-33杂交瘤,其通过融合小鼠骨髓瘤细胞和来自用缀合KLH的溴脱氧尿苷免疫的BALB /c小鼠的脾细胞产生。
Immunogen
与KLH缀合的溴脱氧尿苷。
Application
抗BrdU单克隆抗体可用于免疫染色、 BrdU掺入DNA、 免疫组化以及子宫标记指数。它也被用于研究细胞增殖。
Biochem/physiol Actions
5′-溴-2-脱氧尿苷(BrdU)染色主要用于体内观察肿瘤细胞和其他组织的增殖。
其可与掺入DNA的或与蛋白质载体偶联的BrdU(溴脱氧尿苷)特异性反应。已观察到其与IdU(碘脱氧尿苷)的交叉反应。
Preparation Note
如需连续使用,请保存在0-5EC。对于更长期的存储,可对溶液进行等分并冷冻保存。不建议反复冻融。不建议在无霜冰箱中储存。如果长期储存后发生轻微浑浊,请在使用前通过离心澄清溶液。
Other Notes
本品为纯化产品,由细胞培养杂交瘤生产。
B8434抗-BrdU抗体,小鼠单克隆
克隆 BU-33,由纯化杂交瘤细胞培养物得到。
B8434抗-BrdU抗体,小鼠单克隆
克隆 BU-33,由纯化杂交瘤细胞培养物得到。
Disclaimer
除非我们的产品目录或产品随附的其他公司文档中另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人或动物。
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
动物来源生物产品
此项目有
Alvaro Duque et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 31(42), 15205-15217 (2011-10-22)
As markers of DNA synthesis, [(3)H]thymidine ([(3)H]dT) and the later developed analog bromodeoxyuridine (BrdU) have revolutionized our ability to identify dividing cells and follow their fate in various tissues, including the nervous system. However, the effect of the incorporation of
David H and Huseyin M
Cell Proliferation and Apoptosis (2003)
Dietary Lutein/Zeaxanthin Decreases Ultraviolet B-Induced Epidermal Hyperproliferation and Acute Inflammation in Hairless Mice
Gonzalez S, et al.
The Journal of Investigative Dermatology, 121(2), 399-405 (2003)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| B2531-100UL | 04061833426906 |
| B2531-.2ML | 04061833426890 |