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Merck
CN

D4876

葡聚糖 来源于肠系膜明串珠菌

average mol wt 150,000

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关于此项目

线性分子式:
(C6H10O5)n
化学文摘社编号:
UNSPSC Code:
12352201
NACRES:
NA.25
EC Number:
232-677-5
MDL number:
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biological source

bacterial (Leuconostoc mesenteroides)

Quality Level

form

powder

optical activity

[α]/D 199°

mol wt

average mol wt 150,000

color

white

solubility

H2O: soluble 20 mg/mL

SMILES string

O1C(C(C(C(C1CO)O)O)O)OCC2OC(C(C(C2O)O)O)OCC(O)C(O)C(O)C(O)C=O

InChI

1S/C18H32O16/c19-1-5(21)9(23)10(24)6(22)3-31-17-16(30)14(28)12(26)8(34-17)4-32-18-15(29)13(27)11(25)7(2-20)33-18/h1,5-18,20-30H,2-4H2

InChI key

FZWBNHMXJMCXLU-UHFFFAOYSA-N

Application

右旋糖酐在许多应用中用作血小板聚集剂、血浆增容剂、渗透压调节剂、稳定剂、器官分离介质、基质成分、共聚物、微载体、结合剂、粘度调节剂、抗血栓药、润滑剂和物理结构成分。右旋糖酐可用作长的亲水性间隔臂,以改善结合/结合蛋白的性能(自由活动)。右旋糖酐可衍生化用于生物传感器系统。右旋糖酐 150 可用于研究铁转运至细胞、细胞膜通透性增加和红细胞聚集。
将右旋糖酐用作长的亲水性间隔臂提高了作用于大分子的固定化蛋白质的性能。

Preparation Note

除了最高分子量的葡聚糖D5501(分子量范围= 500万至4,000万),其他葡聚糖都具有非常好的水溶性。 Sigma测试显示,葡聚糖在水中的溶解浓度通常超过30mg/ml。葡聚糖也易溶于DMSO、甲酰胺、乙二醇和甘油。中性-水性葡聚糖溶液可通过在110-115oC下高压灭菌30至45分钟进行灭菌。葡聚糖在高温下可以被强酸水解。葡聚糖的末端还原性端基可在碱性溶液中氧化。

Other Notes

为了全面了解我们针对客户研究提供的各种葡聚糖产品,建议您访问我们的碳水化合物分类页面。


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存储类别

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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实验方案

葡聚糖是葡萄糖酐聚合物。它由大约 95% 的alpha-D-(1-6)键合组成。其余的 a (1-3) 键合构成了葡聚糖的分支。分支长度的冲突数据意味着平均分支长度小于三个葡萄糖单位。但是,其他方法表明存在大于 50 个葡萄糖单位的分支。

Dextran polymer details: composed mainly of alpha-D-(1-6) linkages with varied branch lengths.

相关内容

Dextrans are polysaccharides with molecular weights ≥1,000 Dalton, featuring a linear backbone of α-linked d-glucopyranosyl repeating units.


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Iron (Fe) is an essential and important trace element for animals. In order to study its metabolism and relationship with hepcidin, piglet models of Fe-deficiency and Fe-overload were established by intramuscular injection with different doses of Fe-dextran (150 mg Fe/ml)
Carlos Tassa et al.
Accounts of chemical research, 44(10), 842-852 (2011-06-15)
Advances in our understanding of the genetic basis of disease susceptibility coupled with prominent successes for molecular targeted therapies have resulted in an emerging strategy of personalized medicine. This approach envisions risk stratification and therapeutic selection based on an individual's
Marco R Celio et al.
The Journal of comparative neurology, 521(14), 3133-3153 (2013-06-22)
A solitary cluster of parvalbumin-positive neurons--the PV1 nucleus--has been observed in the lateral hypothalamus of rodents. In the present study, we mapped the efferent connections of the PV1 nucleus using nonspecific antero- and retrograde tracers in rats, and chemoselective, Cre-dependent



全球贸易项目编号

货号GTIN
D4876-100G04061833033050
D4876-1KG04061826754269
D4876-500G04061833585771
D4876-50G04061833585788