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F5135

N-[3-(2-呋喃基)丙烯酰基]-亮氨酸-甘氨酸-脯氨酸-丙氨酸

Name: N-[3-(2-呋喃基)丙烯酰基]-亮氨酸-甘氨酸-脯氨酸-丙氨酸
Brand: SIGMA

collagenase substrate, chromogenic

别名:

FALGPA, N-[3-(2-呋喃基)丙烯酰基]-L-亮氨酸-甘氨酸-L-脯氨酸-L-丙氨酸

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关于此项目

经验公式（希尔记法）:

C₂₃H₃₂N₄O₇

化学文摘社编号:

78832-65-2

分子量:

476.52

UNSPSC Code:

12352202

PubChem Substance ID:

329799652

NACRES:

NA.32

MDL number:

MFCD00133552

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属性

产品名称

N-[3-(2-呋喃基)丙烯酰基]-亮氨酸-甘氨酸-脯氨酸-丙氨酸,

Quality Level

200

UniProt accession no.

Q02111

storage temp.

−20°C

SMILES string

CC(C)C[C@H](NC(=O)\C=C\c1ccco1)C(=O)NCC(=O)N2CCC[C@H]2C(=O)N[C@@H](C)C(O)=O

InChI

1S/C23H32N4O7/c1-14(2)12-17(26-19(28)9-8-16-6-5-11-34-16)21(30)24-13-20(29)27-10-4-7-18(27)22(31)25-15(3)23(32)33/h5-6,8-9,11,14-15,17-18H,4,7,10,12-13H2,1-3H3,(H,24,30)(H,25,31)(H,26,28)(H,32,33)/b9-8+/t15-,17-,18-/m0/s1

InChI key

ZLFQNOJSYZSINX-PVJKAEHXSA-N

Gene Information

mouse ... Prkcq(18761)

说明

General description

N-[3-(2-呋喃基)丙烯酰基]-亮氨酸-甘氨酸-脯氨酸-丙氨酸或FALGPA是一种类似于胶原蛋白一级结构的合成物质，可以被所有已知的胶原酶水解。

胶原酶的底物。

Application

N-[3-(2-呋喃基)丙烯酰基]-亮氨酸-甘氨酸-脯氨酸-丙氨酸已用于采用GBS（B组链球菌）USF704进行的FALGPA检测。

Biochem/physiol Actions

N-[3-(2-呋喃基)丙烯酰基]-亮氨酸-甘氨酸-脯氨酸-丙氨酸或FALGPA可以被胶原酶水解，水解的最适pH为7.4。

Packaging

无底玻璃瓶。内含物在插入的融合锥体内。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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实验方案

使用FALGPA（N-（3- [2-呋喃基]丙烯酰基）-Leu-Gly-Pro-Ala）进行的胶原酶酶法检测（EC 3.4.24.3）

在测定胶原酶活性时，使用N-（3-[2-呋喃基]丙烯酰基）-Leu-Gly-Pro-Ala在345nm处进行连续分光光度法测定。胶原酶水解胶原肽键。

Enzymatic Assay of Collagenase (EC 3.4.24.3) using FALGPA (N-(3-[2-Furyl]acryloyl)-Leu-Gly-Pro-Ala)

To measure collagenase activity, N-(3-[2-Furyl]acryloyl)-Leu-Gly-Pro-Ala is used in a continuous spectrophotometric rate determination at 345 nm. Collagenase hydrolyzes collagen peptide bonds.

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全球贸易项目编号

货号	GTIN
F5135-100MG	04061833618080
F5135-25MG	04061833618097
F5135-5MG	04061833618103