Monoclonal Anti-Granulocyte Colony Stimulating Factor antibody produced in mouse

recombinant human granulocyte colony stimulating factor.

Mature myeloid cells are derived from bone-marrow derived precursor cells by the activity of three colony stimulating factors, granulocyte/macrophage colony-stimulating factor (GM-CSF), macrophage colony-stimulating factor (M-CSF) and granulocyte colony-stimulating factor (G-CSF). The expression of G-CSF is the result of activation of pathways in response to tumor necrosis factor-α, LPS and toll-like receptor ligands. The main functions of G-CSF include the generation of neutrophils and induction of the circulation of hematopoietic stem cells from the bone marrow.

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing carbohydrates.

Purified using protein G.

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