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Merck
CN

N7505

β-烟酰胺腺嘌呤二核苷酸2′-磷酸,还原型 四钠盐 水合物

≥97% (HPLC)

别名:

β-NADPH, 2′-NADPH 水合物, NADPH Na 4, TPNH2 Na4, 磷酸二氢烟酰胺腺嘌呤二核苷酸 四钠盐, 还原型三磷酸吡啶核苷酸 四钠盐, 还原型辅酶 II 四钠盐

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关于此项目

经验公式(希尔记法):
C21H26N7Na4O17P3 · xH2O
化学文摘社编号:
分子量:
833.35 (anhydrous basis)
NACRES:
NA.51
PubChem Substance ID:
UNSPSC Code:
41106305
EC Number:
220-163-3
MDL number:
Form:
powder
Assay:
≥97% (HPLC), ≥97% (spectrophotometric assay)
Solubility:
10 mM NaOH: soluble 50 mg/mL, clear
Biological source:
chicken
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biological source

chicken

Quality Level

assay

≥97% (HPLC), ≥97% (spectrophotometric assay)

form

powder

solubility

10 mM NaOH: soluble 50 mg/mL, clear

storage temp.

−20°C

SMILES string

[Na+].[Na+].[Na+].[Na+].NC(=O)C1=CN(C=CC1)[C@H]2O[C@@H](COP([O-])(=O)OP([O-])(=O)OC[C@H]3O[C@H]([C@H](OP([O-])([O-])=O)[C@@H]3O)n4cnc5c(N)ncnc45)[C@H](O)[C@@H]2O

InChI

1S/C21H30N7O17P3.4Na/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(44-46(33,34)35)14(30)11(43-21)6-41-48(38,39)45-47(36,37)40-5-10-13(29)15(31)20(42-10)27-3-1-2-9(4-27)18(23)32;;;;/h1,3-4,7-8,10-11,13-16,20-21,29-31H,2,5-6H2,(H2,23,32)(H,36,37)(H,38,39)(H2,22,24,25)(H2,33,34,35);;;;/q;4*+1/p-4/t10-,11+,13-,14+,15-,16+,20-,21+;;;;/m0..../s1

InChI key

WYWWVJHQDVCHKF-MPUNMZHWSA-J

Biochem/physiol Actions

β-烟酰胺腺嘌呤二核苷酸2′-磷酸(NADP+)和β-还原型烟酰胺腺嘌呤二核苷酸2′-磷酸(NADPH)包含辅酶氧化还原对(NADP+:NADPH),参与多种酶催化的氧化还原反应。NADP+/NADPH氧化还原对促进合成代谢反应中的电子转移,例如脂质和胆固醇的生物合成以及脂肪酰基链的延长。 NADP+/NADPH氧化还原对可用于多种抗氧化机制,从而保护抵抗反应性氧化物质的积累。NADPH 是通过戊糖磷酸途径(PPP)在体内产生的。
NADPH是许多氧化还原酶(包括一氧化氮合成酶)的电子供体和辅助因子。

Preparation Note

化学还原

Other Notes

根据固体重量包装。


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存储类别

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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分析证书(COA)

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Yan Cai et al.
Experimental neurology, 216(2), 342-356 (2009-01-27)
DCX-immunoreactive (DCX+) cells occur in the piriform cortex in adult mice and rats, but also in the neocortex in adult guinea pigs and rabbits. Here we describe these cells in adult domestic cats and primates. In cats and rhesus monkeys
Berg, J.M., et al.
Biochemistry (5th Edition) (2002)
Kun Xiong et al.
Experimental neurology, 211(1), 271-282 (2008-04-02)
Doublecortin-immunoreactive (DCX+) cells were detected across the allo- and neo-cortical regions in the adult guinea pig cerebrum, localized to layer II specifically at its border with layer I. The density of labeled cells declined with age, whereas no apparent apoptotic



全球贸易项目编号

货号GTIN
N7505-100MG04061835558131
N7505-250MG04061835558148
N7505-1G04061835512836
N7505-25MG04061835558155
N7505-500MG04061835512843