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Rosetta siRNA设计算法通过优化siRNA序列来降低脱靶效应并提高RNAi的性能。
无论新一代测序 (NGS) 平台如何变化，都需要通用和索引接头序列来正确组装样品片段。
如果您计划进行分子诊断(MDx)商业化，开发实验室开发试验(LDT)，或进行治疗学临床前研究，最终的成品试剂盒、检测试剂或药品必须具有非凡的质量水平，符合严苛的监管或研究标准。
相关内容
通过强大的 RNA 干扰科技，可使用合成的小干扰 RNA (siRNA) 实现成功的基因沉默。研究人员正通过让这些长度通常为 19-23 个碱基的小型合成寡核苷酸靶向特定的目标基因，发现基因功能、阐明通路并筛选潜在的新药靶点。
MISSION阳性对照siRNA采用Rosetta siRNA设计算法，可作为所有siRNA沉默实验的理想互补选择。所有MISSION阳性对照siRNA均已通过性能验证，让您可腾出更多时间沉默自己的目标基因，无需为优化内参花费太多时间。
如果您因使用其他厂商的定制接头而饱受接头二聚体之苦，可转用我们的新一代测序寡核苷酸（NGSO）作为优化解决方案。
Leonel Armas-López et al.
Oncotarget, 8(40), 67056-67081 (2017-10-06)
Several homeobox-related gene (HOX) transcription factors such as mesenchyme HOX-2 (MEOX2) have previously been associated with cancer drug resistance, malignant progression and/or clinical prognostic responses in lung cancer patients; however, the mechanisms involved in these responses have yet to be
Fuqiang Chen et al.
Nature methods, 8(9), 753-755 (2011-07-19)
Zinc-finger nucleases (ZFNs) have enabled highly efficient gene targeting in multiple cell types and organisms. Here we describe methods for using simple ssDNA oligonucleotides in tandem with ZFNs to efficiently produce human cell lines with three distinct genetic outcomes: (i)
T N Wiegner et al.
Marine pollution bulletin, 114(2), 952-961 (2016-11-22)
Spatial and temporal patterns of coastal microbial pollution are not well documented. Our study examined these patterns through measurements of fecal indicator bacteria (FIB), nutrients, and physiochemical parameters in Hilo Bay, Hawai'i, during high and low river flow. >40% of
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