General description
GlycoProfile™labeling kit专门设计用于高效地使用2-氨基苯甲酰胺（2-AB）或2-氨基苯甲酸（氨茴酸；2-AA）来对N-连接、O-连接、及糖基磷脂酰肌醇（GPI）锚定的多糖进行标记。这些小荧光素可增强多糖的光谱吸收，提高HPAE（高性能阴离子交换色谱）、HPLC、及ESI-MS（电喷射质谱）等方法标记多糖的检测效果。其结合非常可靠，所得的染料-多糖轭合物也很稳定，在标记后的分析过程中不会发生降解。
Application
GlycoProfile™ 2-AA Labeling Kit has been used in the labeling of fluorescently derivatized N-glycans from chinese hamster ovary CHO cells.
While 2-AB is slightly less sensitive than 2-AA, it is suitable for downstream glycan analysis by HPAE, HPLC and ESI-MS. Although suitable for the same applications, 2-AA is better suited for SDS-PAGE.
Legal Information
GlycoProfile is a trademark of Sigma-Aldrich Co. LLC
仅试剂盒组分
产品编号
说明
- Anthranilic acid (2-AA) 2 x 6
- Dimethyl sulfoxide (DMSO) 2 x 350
- Acetic acid, glacial 2 x 200
- Reductant (sodium cyanoborohydride) 2 x 6
signalword
Danger
hcodes
Hazard Classifications
Eye Dam. 1
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
302.0 °F - closed cup
flash_point_c
150 °C - closed cup
法规信息
监管及禁止进口产品
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商品
蛋白质的结构修饰对于活细胞是必不可少的。发生调节异常时，它们往往是会引发疾病。聚糖是生物系统中许多结构变异的原因，它们在细胞表面的表现通常被称为“糖”。
Glycoprofile Labeling Kits efficiently label glycans for glycan analysis, offering flexibility in choice of labeling.
Glycans play a key role in protein structure and disease; representation on cell surfaces is the glycome.
相关内容
Glycobiology and Glycoproteomics Brochure
Modulation of IgG1 immunoeffector function by glycoengineering of the GDP-fucose biosynthesis pathway
Kelly RM, et al.
Biotechnology and Bioengineering, 115(3), 705-718 (2018)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| PP0530-1KT | 04061836686925 |