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S1141

精胺 四盐酸盐

BioReagent, Molecular Biology

别名:

N,N′-双(3-氨丙基)-1,4-丁二胺 四盐酸盐

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关于此项目

经验公式（希尔记法）:
C10H26N4 · 4HCl
化学文摘社编号:
306-67-2
分子量:
348.18
UNSPSC Code:
12352116
NACRES:
NA.52
PubChem Substance ID:
24899462
EC Number:
206-189-8
Beilstein/REAXYS Number:
3911771
MDL number:
MFCD00012914
Form:
solid
Quality level:
300
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grade

Molecular Biology

Quality Level

300

product line

BioReagent

form

solid

mp

310-311 °C (dec.) (lit.)

solubility

H2O: soluble 100 mg/mL, clear, colorless to light yellow

foreign activity

DNase, RNase, protease, NICKase, none detected

storage temp.

room temp

SMILES string

Cl.Cl.Cl.Cl.NCCCNCCCCNCCCN

InChI

1S/C10H26N4.4ClH/c11-5-3-9-13-7-1-2-8-14-10-4-6-12;;;;/h13-14H,1-12H2;4*1H

InChI key

XLDKUDAXZWHPFH-UHFFFAOYSA-N

General description

精胺是一种多胺，参与细胞代谢和 DNA 稳定。在分子生物学中，它可用于纯化 DNA 的缓冲液。

Application

用于从低盐缓冲液中沉淀 DNA。

Biochem/physiol Actions

多胺位点混合型 NMDA 激动-拮抗剂。在细胞增殖和分化中发挥作用；抑制神经元一氧化氮合成酶 (nNOS)。
多胺位点混合型 NMDA 激动-拮抗剂。在高浓度 (1mM) 下观察到神经保护作用，而在低浓度下则观察到神经毒性。它在番木鳖碱-不敏感性甘氨酸位点能够增强激动剂效应。在细胞增殖和分化中发挥作用；抑制神经元一氧化氮合成酶 (nNOS)。

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signalword

Warning

pictograms

Exclamation mark
GHS07

hcodes

H315,H319

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCCG9744
BCCG6714
BCCF5684
BCCF5352
BCCC8318

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实验方案

Spermine Tetrahydrochloride for Molecular Biology

This product is suitable for DNA precipitation from low salt aqueous buffers. It has been tested for the absence of proteases and nucleases.

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Product Information Sheet - S1141
D M Hougaard et al.
The Biochemical journal, 238(1), 43-47 (1986-08-15)
Two recently developed fluorescence cytochemical methods, specific for spermidine and spermine, were used to localize polyamines in the endocrine pancreas. The polyamines were restricted to the insulin-producing beta-cells and were mainly associated with the secretory granules. Chemical polyamine determinations carried
Binh V Vu et al.
PloS one, 7(12), e51863-e51863 (2013-01-04)
While most nucleic acids are intracellular, trace amounts of deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), including micro RNAs, can also be found in peripheral blood. Many studies have suggested the potential utility of these circulating nucleic acids in prenatal
Aracely A Lutes et al.
Proceedings of the National Academy of Sciences of the United States of America, 108(24), 9910-9915 (2011-05-06)
Speciation in animals commonly involves an extrinsic barrier to genetic exchange followed by the accumulation of sufficient genetic variation to impede subsequent productive interbreeding. All-female species of whiptail lizards, which originated by interspecific hybridization between sexual progenitors, are an exception
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全球贸易项目编号

货号GTIN
SAB1309036-400UL04065272322645
S1141-10G04061833613283
S1141-1G04061836908836
S1141-5G04061836908867