biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 53 kDa
species reactivity
human, mouse
concentration
~1 mg/mL
technique(s)
ELISA: 1:5000, immunofluorescence: 1:100-1:500
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... GLP1R(2740)
General description
抗-GLP1R抗体可检测总GLP1R蛋白的内源性水平。
胰高血糖素样肽1受体(GLP1R)蛋白属于B类G蛋白偶联受体(GPCR)分泌素家族。这一经典七重跨膜蛋白在心血管系统中大量表达。GLP1R基因位于人染色体6p21上。抗GLP1R抗体检测总GLP1R蛋白的内源性水平。
Immunogen
该抗血清是针对衍生自人GLP1R的合成肽而生成的。
免疫原范围： 101-150
免疫原范围： 101-150
Application
兔抗GLP1R抗体可用于免疫组织化学染色分析。
Biochem/physiol Actions
胰高血糖素样肽1受体(GLP1R)蛋白参与蛋白激酶A (PKA)、磷脂酰肌醇3-激酶(PI3K)、MEK1/2和内皮型一氧化氮合酶(eNOS)通路的激活。因此，它在减少细胞凋亡、改善能量代谢、减轻心肌细胞炎症、舒张心肌动脉血管等方面发挥关键作用。GLP1R的N端胞外结构域参与配体结合。GLP1R基因的改变可能增加冠心病(CAD)的风险。
Features and Benefits
完放心地使用我们的抗体。如果抗体在您的申请的研究中不起作用，我们将全额退款或安排替代抗体。了解更多信息。
Physical form
兔IgG，溶于磷酸盐缓冲液（不含Mg2+和Ca2+），pH 7.4,150mM NaCl，0.02％叠氮化钠和50％甘油中。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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存储类别
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
低风险生物材料
常规特殊物品
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全球贸易项目编号
| 货号 | GTIN |
|---|---|
| SAB4501220-100UG | 04061837744464 |