form
aqueous solution
Quality Level
β-glucuronidase activity
≥100,000 units/mL
secondary activity
≤8,000 units/mL sulfatase
storage temp.
2-8°C
Application
来自鲍鱼的β-葡糖苷酸已用作标准品，用于评估其在苯并二氮卓（benzodiazepine）液相色谱-质谱（LC-MS/MS）验证测试中的性能。
Biochem/physiol Actions
β-葡糖醛酸糖苷酶是存在于多种动物、植物和细菌中的酶。它催化β-葡糖苷酸偶联物和植物葡糖苷酸的水解。β-葡糖醛酸糖苷酶是糖基水解酶（GH）家族2的一员，也是一种同型四聚体糖蛋白。它促进葡糖苷酸上葡糖醛酸的去除，并有助于肝脏代谢酶排泄内源和外来物质。
Physical form
以含有0.85%NaCl和0.02%叠氮化钠的水溶液形式提供
Other Notes
在37℃，pH 3.8（30分钟检测）条件下，一个Sigma或改良的Fishman单位可每小时从酚酞葡糖苷酸中释放1.0 μg酚酞。
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signalword
Danger
hcodes
pcodes
Hazard Classifications
Resp. Sens. 1
存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
低风险生物材料
此项目有
商品
β-glucuronidase (GUS) enzymes are utilized to hydrolyze glucuronide (gluc) drug metabolites to the parent drug, facilitating analysis by LC-MS/MS.
Francesco Candeliere et al.
Frontiers in microbiology, 13, 826994-826994 (2022-03-22)
β-glucuronidases (GUS) of intestinal bacteria remove glucuronic acid from glucoronides, reversing phase II metabolism of the liver and affecting the level of active deconjugated metabolites deriving from drugs or xenobiotics. Two hundred seventy-nine non-redundant GUS sequences are known in the
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| SRE0037-10ML | 04061838087775 |
| SRE0037-25ML | 04061838107589 |
| SRE0037-50ML | 04061838114945 |