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Merck
CN

T1512

四咪唑 盐酸盐

powder, ≥99% (TLC)

别名:

(±)-2,3,5,6-四氢-6-苯基咪唑并[2,1-b]噻唑 盐酸盐

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关于此项目

经验公式(希尔记法):
C11H12N2S · HCl
化学文摘社编号:
分子量:
240.75
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352202
EC Number:
225-799-5
MDL number:
Beilstein/REAXYS Number:
4358989
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产品名称

四咪唑 盐酸盐, phosphatase inhibitor

biological source

synthetic (organic)

Quality Level

description

alkaline phosphatase inhibitor

assay

≥99% (TLC)

form

powder

mp

266-267 °C (lit.)

solubility

water: 50 mg/mL, clear, colorless

SMILES string

Cl[H].C1CN2CC(N=C2S1)c3ccccc3

InChI

1S/C11H12N2S.ClH/c1-2-4-9(5-3-1)10-8-13-6-7-14-11(13)12-10;/h1-5,10H,6-8H2;1H

InChI key

LAZPBGZRMVRFKY-UHFFFAOYSA-N

Application

四咪唑衍生物作为碱性磷酸酶抑制剂的结构-活性关系。
适于抑制各种哺乳动物碱性磷酸酶(例如,肝、肾、胎盘、骨和肿瘤)。肠道碱性磷酸酶仅受到轻微的抑制。

Other Notes

外消旋形式的左旋咪唑。


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pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Kinetics and inhibition of alkaline phosphatases from canine tissues.
H Van Belle
Biochimica et biophysica acta, 289(1), 158-168 (1972-11-10)
Karla Opperman et al.
Genetics, 199(2), 497-509 (2014-12-10)
The L1CAM family of cell adhesion molecules is a conserved set of single-pass transmembrane proteins that play diverse roles required for proper nervous system development and function. Mutations in L1CAMs can cause the neurological L1 syndrome and are associated with
Mariana G Simões et al.
BMC developmental biology, 14, 49-49 (2015-01-01)
Zebrafish are able to regenerate many of its tissues and organs after damage. In amphibians this process is regulated by nerve fibres present at the site of injury, which have been proposed to release factors into the amputated limbs/fins, promoting



全球贸易项目编号

货号GTIN
T1512-5G04061837337697
T1512-10G04061833632253
T1512-2G04061833632260