产品名称
四咪唑 盐酸盐, phosphatase inhibitor
biological source
synthetic (organic)
Quality Level
description
alkaline phosphatase inhibitor
assay
≥99% (TLC)
form
powder
mp
266-267 °C (lit.)
solubility
water: 50 mg/mL, clear, colorless
SMILES string
Cl[H].C1CN2CC(N=C2S1)c3ccccc3
InChI
1S/C11H12N2S.ClH/c1-2-4-9(5-3-1)10-8-13-6-7-14-11(13)12-10;/h1-5,10H,6-8H2;1H
InChI key
LAZPBGZRMVRFKY-UHFFFAOYSA-N
Application
四咪唑衍生物作为碱性磷酸酶抑制剂的结构-活性关系。
适于抑制各种哺乳动物碱性磷酸酶(例如,肝、肾、胎盘、骨和肿瘤)。肠道碱性磷酸酶仅受到轻微的抑制。
Other Notes
外消旋形式的左旋咪唑。
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signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Kinetics and inhibition of alkaline phosphatases from canine tissues.
H Van Belle
Biochimica et biophysica acta, 289(1), 158-168 (1972-11-10)
Karla Opperman et al.
Genetics, 199(2), 497-509 (2014-12-10)
The L1CAM family of cell adhesion molecules is a conserved set of single-pass transmembrane proteins that play diverse roles required for proper nervous system development and function. Mutations in L1CAMs can cause the neurological L1 syndrome and are associated with
Mariana G Simões et al.
BMC developmental biology, 14, 49-49 (2015-01-01)
Zebrafish are able to regenerate many of its tissues and organs after damage. In amphibians this process is regulated by nerve fibres present at the site of injury, which have been proposed to release factors into the amputated limbs/fins, promoting
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| T1512-5G | 04061837337697 |
| T1512-10G | 04061833632253 |
| T1512-2G | 04061833632260 |
