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{"sheet":"Cu CN","index":0,"n_rows":40,"n_cols":7,"rows_kept":40,"cut":false,"hidden":false,"merged":[[0,0,0,6],[2,0,3,6],[1,0,1,6],[7,2,7,5],[17,1,17,6]]}
["Cu C-N Kit: 6 Ligands, 4 solvents, 1 base"]
["6 x 4 Design"]
["                                1. Enter information in GREEN BOXES 2. Hit Enter 3. Print"]
[]
[null,null,"Name","MW","umol","rxn conc"]
[null,null,"Aryl Halide",234,10,"0.1 M"]
[null,null,"Amine",59,15]
[null,null,"Typically 15 umol of amine is used. 15 umol (entered above) is recommended but can be modified in cell E7"]
[]
[]
[null,"Aryl Halide (mg)","Amine (mg)","Base (3 equiv) ","Solvent (0.1M)","Solvent Amount (uL)"]
["Vial One - Solution A: DMAc",{"$f":"('WorkSheet 12x2'!D22)","v":16.847999999999999},{"$f":"('WorkSheet 12x2'!$D$21)","v":6.3719999999999999},"K3PO4: Preweighed ","DMAc",{"$f":"(100*6*1.2)-($B$12+$C$12+45)","v":651.78}]
["Vial Two - Solution B: Toluene",{"$f":"('WorkSheet 12x2'!$D$22)","v":16.847999999999999},{"$f":"('WorkSheet 12x2'!$D$21)","v":6.3719999999999999},"K3PO4: Preweighed ","Toluene",{"$f":"(100*6*1.2)-($B$12+$C$12+45)","v":651.78}]
["Vial Three - Solution C: Dioxane",{"$f":"('WorkSheet 12x2'!$D$22)","v":16.847999999999999},{"$f":"('WorkSheet 12x2'!$D$21)","v":6.3719999999999999},"K3PO4: Preweighed ","Dioxane",651.78]
["Vial Four- Solution D: DMSO",{"$f":"('WorkSheet 12x2'!$D$22)","v":16.847999999999999},{"$f":"('WorkSheet 12x2'!$D$21)","v":6.3719999999999999},"K3PO4: Preweighed ","DMSO",651.78]
[]
[]
["CuI solution","Add 472 uL DMSO to Cu(TBAI)2 vial, shake until dissolved.  Dose 20 uL to each of 24 reaction vials as LAST step"]
[]
["Supplies to load Inertion Box: ","1 ampule DMAc","1 ampule Toluene","1 ampule DMSO"]
[null,"1 ampule Dioxane","CuI vial","stock solutioon vials containing your weighed substrates"]
["Equipment Needed:","4 syringes with needles","pipette with tips"]
["0. Preheat hot plate to 100 °C"]
["1. Place reaction block and lid in inertion box. \"Purge\" box 5 minutes-continue flow of gas"]
["2. Weigh substrates, label Substrate Mix A, B, C, and D.  ADD STIRBARS!"]
["3. Load inertion box with substrates, ampules, and capped ligands. \"Purge\" box 5 minutes-continue flow of gas",null,null,null,"                                                             Detailed user guide available at SigmaAldrich.com"]
["4. Make stock solutions according to recipe above using needle and syringe (get as close as you can to volume)",null,null,null,null,"\"save as\" pdf to append to ELN"]
["5. Allow mixtures to stir into solution. CAREFULLLY Remove cap mat from ligands"]
["6. using pipette add 100 uL \"DMAc Solution A\" to vials A1-A6"]
["7. Add 100 uL \"Toluene Solution B\" to vials B1-B6"]
["8. Add 100 uL \"Dioxane Solution C\" to vials C1-C6"]
["9. Add 100 uL \"DMSO Solution D\" to vials D1-D6"]
["10. Add 20 uL CuI DMSO solution to each of the 24 reaction vials",null,null,"    r"]
["11. Seal block and heat to 100 °C o/n"]
[]
[null,1,2,3,4,5,6]
["Vial One - Solution A: DMAc","DMPAO","DiMeOPAO","2,6-DFPAO","PFPAO","3,5-BisCF3PAO","2-F-6-PIP-S-PAO"]
["Vial Two - Solution B: Toluene","DMPAO","DiMeOPAO","2,6-DFPAO","PFPAO","3,5-BisCF3PAO","2-F-6-PIP-S-PAO"]
["Vial Three - Solution C: Dioxane","DMPAO","DiMeOPAO","2,6-DFPAO","PFPAO","3,5-BisCF3PAO","2-F-6-PIP-S-PAO"]
["Vial Four- Solution D: DMSO","DMPAO","DiMeOPAO","2,6-DFPAO","PFPAO","3,5-BisCF3PAO","2-F-6-PIP-S-PAO"]

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["6 Catalysts x 4 Solvents"]
["1.) The 24 well plate has 6 predosed catalysts arranged below:"]
["24 Well Plate"]
[null,1,2,3,4,5,6]
["A"]
[]
[]
["B"]
[]
[]
["C"]
[]
[]
["D"]
[]
[]
[]
["2.) In 2 appropriately sized & labelled vials, weigh out:",null,null,null,null,"umol base/ rxn","Rxn Conc "]
["Vial","Substrate","Name","mg",null,30,{"$f":"'Cu CN'!F6","v":"0.1 M"}]
[1,1,{"$f":"'Cu CN'!$C$6","v":"Aryl Halide"},{"$f":"'Cu CN'!E$6*'Cu CN'!D$6*1.2*6/1000","v":16.847999999999999}]
[null,2,{"$f":"'Cu CN'!$C$7","v":"Amine"},{"$f":"'Cu CN'!E$7*'Cu CN'!D7*1.2*6/1000","v":6.3719999999999999},null,"uMol Substrate 1/ rxn","umol substrate 2/ rxn"]
[2,1,{"$f":"'Cu CN'!$C$6","v":"Aryl Halide"},{"$f":"'Cu CN'!E$6*'Cu CN'!D$6*1.2*6/1000","v":16.847999999999999}]
[null,2,{"$f":"'Cu CN'!$C$7","v":"Amine"},{"$f":"'Cu CN'!E$7*'Cu CN'!D7*1.2*6/1000","v":6.3719999999999999},null,{"$f":"'Cu CN'!E6","v":10},{"$f":"'Cu CN'!E7","v":15}]