biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
species reactivity
human, rat, mouse
technique(s)
immunofluorescence: suitable, immunohistochemistry: suitable, indirect ELISA: suitable, western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... KCNK18(338567)
General description
Potassium two pore domain channel subfamily K member 18 (KCNK18) or TRESK is part of the potassium channel family. It is expressed in trigeminal and dorsal root ganglions. The protein is activated by calcium signals. The TRESK gene is localized on human chromosome 10q25.3.
Immunogen
TRESK antibody was raised against a 17 amino acid peptide from near the center of human TRESK.
Biochem/physiol Actions
Potassium two pore domain channel subfamily K member 18 (KCNK18) or TRESK contributes to background K+ currents in sensory neurons. Mutations in the gene encoding it have been associated with familial migraine with aura.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Supplied in PBS with 0.02% sodium azide.
Other Notes
The action of this antibody can be blocked using blocking peptide SBP3500141.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
10 - Combustible liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
低风险生物材料
常规特殊物品
此项目有
TRESK: the lone ranger of two-pore domain potassium channels.
Enyedi P
Molecular and Cellular Endocrinology (2012)
Identification of novel small molecule modulators of K2P18.1 two-pore potassium channel.
Bruner JK
European Journal of Pharmacology (2014)
Involvement of gap junction channels in the pathophysiology of migraine with aura
Denis Sarrouilhe
Frontiers in Physiology (2014)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| SBP3500141-0.05MG | 04061832167435 |
| SAB3500141-100UG | 04061832494579 |