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B103608

γ-Butyrolactone

Name: γ-Butyrolactone
Brand: ALDRICH

ReagentPlus^®, ≥99%

Synonym(s):

gamma-Butyrolactone, γ-Hydroxybutyric acid lactone, 4-Hydroxybutyric acid lactone, GBL

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About This Item

Empirical Formula (Hill Notation):

C₄H₆O₂

CAS Number:

96-48-0

Molecular Weight:

86.09

UNSPSC Code:

12352100

NACRES:

NA.22

PubChem Substance ID:

24891553

EC Number:

202-509-5

Beilstein/REAXYS Number:

105248

MDL number:

MFCD00005386

Assay:

≥99%

Form:

liquid

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Properties

vapor density

3 (vs air)

Quality Level

200

vapor pressure

1.5 mmHg ( 20 °C)

product line

ReagentPlus^®

assay

≥99%

form

liquid

autoignition temp.

851 °F

expl. lim.

16 %

drug control

Pszichotróp anyag / Psychotropic Substance (Hungary), 78/2022. (XII. 28.) BM rendelet

refractive index

n20/D 1.436 (lit.)

bp

204-205 °C (lit.)

mp

−45 °C (lit.)

density

1.12 g/mL at 25 °C (lit.)

SMILES string

O=C1CCCO1

InChI

1S/C4H6O2/c5-4-2-1-3-6-4/h1-3H2

InChI key

YEJRWHAVMIAJKC-UHFFFAOYSA-N

Description

Application

For the introduction of 3-carboxypropyl side chain. Used as a component of electrolyte solutions in batteries and capacitors.

Biochem/physiol Actions

Precursor of γ-hydroxybutyric acid (GHB). It blocks dopamine release by blocking impulse flow in dopaminergic neurons. Pretreatment with γ-butyrolactone allows detection of autoreceptor-induced dopamine release.

Precursor of γ-hydroxybutyric acid (GHB); blocks dopamine release.

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

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pictograms

GHS05,GHS07

signalword

Danger

hcodes

H302,H318,H336

pcodes

P261 - P264 - P271 - P280 - P301 + P312 - P305 + P351 + P338

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - STOT SE 3

target_organs

Central nervous system

Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

208.4 °F - closed cup

flash_point_c

98 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Regulatory Information

易制毒化学品（3类）

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Dual inhibitors of thromboxane A2 synthase and 5-lipoxygenase with scavenging activity of active oxygen species. Synthesis of a novel series of (3-pyridylmethyl)benzoquinone derivatives.

S Ohkawa et al.

Journal of medicinal chemistry, 34(1), 267-276 (1991-01-01)

A novel series of (3-pyridylmethyl)benzoquinone derivatives was molecular designed and synthesized for the dual purpose of inhibiting thromboxane A2 and leukotriene biosynthesis enzymes and scavenging active oxygen species (AOS). They were evaluated for inhibition of TXA2 synthase, inhibition of 5-lipoxygenase

Journal of Power Sources, 43, 195-195 (1993)

The GIRK2 subunit is involved in IS-like seizures induced by GABA(B) receptor agonists.

Monica Blichowski et al.

Epilepsia, 56(7), 1081-1087 (2015-06-03)

Infantile spasms (or IS) is a catastrophic childhood epilepsy that is particularly prevalent in children with Down syndrome. Previously, we have shown that the Ts65Dn (Ts) mouse model of Down syndrome is a useful substrate upon which to develop an

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Global Trade Item Number

SKU	GTIN
B103608-500G	04061837378041
B103608-2.5KG	04061837378027
B103608-20KG	04061837378034
B103608-25G	04061833420492