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Merck
CN

180947

Alginic acid sodium salt

powder

Synonym(s):

Algin, Sodium alginate, Alginate / Alginic acid

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About This Item

CAS Number:
UNSPSC Code:
12162002
NACRES:
NA.23
MDL number:
Technical Service
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biological source

algae (marine)

Quality Level

form

powder

viscosity

15-25 cP, 1 % in H2O

SMILES string

[Na+].[O-]C(=O)C1O[C@H]([C@H]([C@H]([C@@H]1O)O)O)O

InChI

1S/C6H10O7.Na/c7-1-2(8)4(5(10)11)13-6(12)3(1)9;/h1-4,6-9,12H,(H,10,11);/q;+1/p-1/t1-,2-,3-,4?,6+;/m0./s1

InChI key

MSXHSNHNTORCAW-MPGIDXPLSA-M

General description

Alginic acid sodium is a gelling and nontoxic anionic polysaccharide. The carboxylic acid groups on the alginic acid chain, renders it insoluble in water.However, converting alginic acid to its sodium form, enables it to solubilize in water easily.

Application

Alginic acid sodium is used:
  • in combination with chitosan, to fabricate a biodegradable porous scaffold for bone tissue engineering.
  • to study the characteristics of a modified amphiphilic alginate derivative
  • to the study the impact of alginate on the rate of lipid digestion by employing an in vitro digestion model
  • in the preparation of alginate hydrogels
  • as encapsulating agents of microparticles of β-galactosidae


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Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Articles

将基于水凝胶的生物材料用于递送和募集细胞以促进体内组织再生是新生的研究热题。本文讨论了水凝胶在细胞递送和组织再生中的应用。

Chitosan is a naturally occurring polysaccharide ideally suited for use in medical supplies, devices, therapeutics, and diagnostics. The unique natural characteristics of chitosan include its cationic, biocompatible, biodegradable, non-toxic, non-immunogenic, and antimicrobial properties.

Hydrogel-based biomaterials for cell delivery and tissue regeneration applications are discussed.

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Microencapsulation of ?-galactosidase with different biopolymers by a spray-drying process
Estevinho BN, et al.
Food Research International, 64, 134-140 (2014)
Teegarden DM
Polymer Chemistry: Introduction to an Indispensable Science (2004)
Thao Thi Thu Vu et al.
Journal of biomedical materials research. Part B, Applied biomaterials, 100(7), 1980-1988 (2012-08-14)
Alginate hydrogels possess tunable mechanical properties that can mimic soft marrow tissue and present three-dimensional (3D) cues. This study evaluates its utility for supporting leukemic cell growth in vitro and its impact on cell survival, growth, and differentiation. Our results



Global Trade Item Number

SKUGTIN
180947-500G04061838755056
180947-100G04061835561537
180947-250G04061835561544