219991
4-Imidazoleacetic acid hydrochloride
98%
Synonym(s):
(4-Imidazolyl)acetic acid hydrochloride, I4AA
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About This Item
Empirical Formula (Hill Notation):
C5H6N2O2 · HCl
CAS Number:
Molecular Weight:
162.57
UNSPSC Code:
12352005
NACRES:
NA.22
PubChem Substance ID:
EC Number:
221-840-6
Beilstein/REAXYS Number:
3701591
MDL number:
Assay:
98%
Form:
solid
Quality Level
assay
98%
form
solid
mp
218-222 °C (lit.)
solubility
water: soluble 100 mg/mL, clear, faintly yellow
functional group
carboxylic acid
SMILES string
Cl.OC(=O)Cc1c[nH]cn1
InChI
1S/C5H6N2O2.ClH/c8-5(9)1-4-2-6-3-7-4;/h2-3H,1H2,(H,6,7)(H,8,9);1H
InChI key
MWHLCFYPFGFBQO-UHFFFAOYSA-N
Application
4-Imidazoleacetic acid hydrochloride was used in the synthesis of:
- imidazolyl-polyethylenimine modified nanoparticles
- pyridyl and imidazoyl functionalized carboproteins, potential metal ion chelators
Biochem/physiol Actions
Competitive antagonist at GABAC receptors.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Nan Yan et al.
Small (Weinheim an der Bergstrasse, Germany), 15(41), e1903016-e1903016 (2019-08-20)
Developing tumor-responsive diagnosis and therapy strategies for tumor theranostics is still a challenge owing to their high accuracy and specificity. Herein, an AND logic gated-DNA nanodevice, based on the fluorescence nucleic acid probe and polymer-modified MnO2 nanosheets, for glutathione (GSH)-gated
Archana Swami et al.
International journal of pharmaceutics, 335(1-2), 180-192 (2006-12-16)
The derivatives of polyethylenimine (PEI 25 and 750kDa) were synthesized by partially substituting their amino groups with imidazolyl moieties. The series of imidazolyl-PEIs thus obtained were cross-linked with polyethylene glycol (PEG) to get imidazolyl-PEI-PEG nanoparticles (IPP). The component of hydrophobicity
Zihao Wang et al.
Proceedings of the National Academy of Sciences of the United States of America, 105(37), 13793-13798 (2008-09-10)
Protein GlcNAcylation serves as a nutrient/stress sensor to modulate the functions of many nuclear and cytoplasmic proteins. O-GlcNAc cycles on serine or threonine residues like phosphorylation, is nearly as abundant, and functions, at least partially, via its interplay with phosphorylation.
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 219991-5G | 04061833355121 |
| 219991-1G | 04061826696194 |