38534
Polylactic acid
Mw ~60,000
Synonym(s):
Poly(2-hydroxypropionic acid)
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About This Item
form
solid
Quality Level
shelf life
limited shelf life, expiry date on the label
mol wt
Mn ~30,000, Mw ~60,000
SMILES string
[O-]C(=O)C(O)C.[H+]
InChI
1S/C3H6O3/c1-2(4)3(5)6/h2,4H,1H3,(H,5,6)
InChI key
JVTAAEKCZFNVCJ-UHFFFAOYSA-N
General description
Polylactic acid(PLA) is a biodegradable polyester synthesized from lactic acid monomer via ring opening polymerization. Owing to its excellent thermal, mechanical and barrier properties, it is widely used in the field of tissue engineering, drug delivery, and orthopedic devices.
Application
Polylactic acid can be used to prepare tubular scaffolds via the electrospinning method. These scaffolds are applicable in vascular tissue engineering.
It can be used to prepare PLA/polyvinyl alcohol wound dressing membrane through electrospinning and coating method. The coating of PLA improves the mechanical strength of nanofiber and acts as a protective layer to control the release of drug to the wound site.
It can also be used to synthesize free-standing, flexible ultra-thin PLA nanofilms which can act as a matrix for adhesion, spreading, and proliferation of skeletal muscle cells.
It can be used to prepare PLA/polyvinyl alcohol wound dressing membrane through electrospinning and coating method. The coating of PLA improves the mechanical strength of nanofiber and acts as a protective layer to control the release of drug to the wound site.
It can also be used to synthesize free-standing, flexible ultra-thin PLA nanofilms which can act as a matrix for adhesion, spreading, and proliferation of skeletal muscle cells.
Features and Benefits
- Biocompatibility
- Lower toxicity
- Low cost
- Better encapsulation
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Articles
Electrospinning technique applications discussed, emphasizing control of nanofibers and assembly into 3D architectures.
Tong Chen et al.
Carbohydrate polymers, 92(2), 1124-1132 (2013-02-13)
Core-shell structured multifunctional nanocarriers (NCs) of ZnO quantum dots-conjugated gold nanoparticles (Au NPs) as core and amphiphilic hyperbranched block copolymer as shell were synthesized for targeted anticancer drug delivery. The amphiphilic hyperbranched block copolymer contained poly(l-lactide) (PLA) inner arm and
L Pearce McCarty et al.
The Journal of bone and joint surgery. American volume, 95(6), 507-511 (2013-02-15)
A variety of complications associated with the use of poly-L-lactic acid (PLLA) implants, including anchor failure, osteolysis, glenohumeral synovitis, and chondrolysis, have been reported in patients in whom these implants were utilized for labral applications. We report on a large
Zhenxing Fan et al.
Environmental technology, 33(19-21), 2369-2374 (2013-02-12)
Biological nitrate removal using wheat straw and polylactic acid (PLA) as both carbon source and biofilm support was investigated. The results showed that biofilm could develop on the surface of wheat straw within 15 d, the denitrification rate was 0.067
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 38534-5G | 04061831966381 |
| 38534-1G | 04061831966367 |