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About This Item
Linear Formula:
[NH2(CH2)2NH2]:(G=4);dendri PAMAM(NH2)64
CAS Number:
Molecular Weight:
14214.17
UNSPSC Code:
12162002
NACRES:
NA.23
MDL number:
description
amino surface groups
Quality Level
form
solution
mol wt
generation 4.0
feature
core type ethylenediamine core (2-carbon core)
concentration
10 wt. % in methanol
no. Surface Groups
64
refractive index
n20/D 1.348
bp
64.7 °C
density
0.813 g/mL at 25 °C
storage temp.
2-8°C
General description
PAMAM dendrimer, ethylenediamine core, generation 4.0 solution is a poly(amidoamine) that is categorized as a class of dendritic polymers which can be prepared by a two-step interactive reaction that forms generations around the central ethylenediamine core. It consists of nitrogen and amide as functional groups that are structured in regular “branched upon branched” pattern. It is majorly used as a high capacity chelating agent.
Application
PAMAM dendrimer, ethylenediamine core, generation 4.0 solution is used as a compacting agent to bring in the conformational changes in the DNA molecule. It can be attached on the cellulose substrate that acts as a biofunctional surface for potential applications in immonoassays. It is used in MRI contrast agents and in the condensation formation of silica nanospheres.
Physical form
Contains 64 surface primary amino groups
Legal Information
Manufactured by Dendritech®, Inc.
Dendritech is a registered trademark of Dendritech, Inc.
signalword
Danger
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
target_organs
Eyes
Storage Class
3 - Flammable liquids
wgk
WGK 3
flash_point_f
51.8 °F - closed cup
flash_point_c
11 °C - closed cup
ppe
Eyeshields, Faceshields, Gloves
Regulatory Information
危险化学品
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Articles
Replace volatile organic solvents with water due to environmental concerns, overcoming challenges in solubility.
Dendritic chelating agents. 1. Cu (II) binding to ethylene diamine core poly (amidoamine) dendrimers in aqueous solutions
Diallo MS, et al.
Langmuir, 20(7), 2640-2651 (2004)
Felipe Vidal et al.
Molecular pharmaceutics, 13(10), 3395-3403 (2016-08-25)
Polyamidoamine (PAMAM) dendrimers are hyperbranched macromolecules which have been described as one of the most promising drug nanocarrier systems. A key process to understand is their cellular internalization mechanism because of its direct influence on their intracellular distribution, association with
Dendrimer enhanced ultrafiltration. 1. Recovery of Cu (II) from aqueous solutions using PAMAM dendrimers with ethylene diamine core and terminal NH2 groups
Diallo MS, et al.
Environmental Science & Technology, 39(5), 1366-1377 (2005)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 412449-1G | 04061837697135 |
| 412449-2G | 04061837697159 |
| 412449-10G | 04061837697128 |
| 412449-2.5G | 04061837697142 |


