535311
Poly(N-isopropylacrylamide)
Mn ~40,000
Synonym(s):
NIPAM polymer, PNIPAM, Polyacrylamide, polyNIPAM
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About This Item
Linear Formula:
CH3(C6H11NO)nCH3
CAS Number:
NACRES:
NA.23
PubChem Substance ID:
UNSPSC Code:
12162002
MDL number:
Quality Level
mol wt
Mn 20,000-60,000, Mn ~40,000
mp
96 °C
SMILES string
CC(C)NC(=O)C=C
InChI
1S/C6H11NO/c1-3-5-7-6(8)4-2/h4H,2-3,5H2,1H3,(H,7,8)
InChI key
WDFKEEALECCKTJ-UHFFFAOYSA-N
Application
Thermosensitive polymer, can be used to form a hydrogel. Aqueous polymer solution undergoes a phase transition from a soluble to an insoluble state when the temperature is raised to ca. 32 °C.
Physical form
Thermosensitive polymer, hydrogel
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Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Articles
通过调整的理化特性，药物递送系统可根据需要设计为可递送治疗分子的智能系统。了解有关刺激响应材料药物递送应用的更多信息。
组织工程已成为治疗受损或患病的器官和组织（例如血管和尿囊）的关键治疗工具。
Biomaterials science integrates smart materials into biological research, requiring a deep understanding of biological systems.
Yan Xia et al.
Chemical communications (Cambridge, England), 49(25), 2566-2568 (2013-02-21)
Site-specific protein conjugates with RAFT polymers were synthesized using expressed protein ligation. Stable micelles were formed from both linear block copolymer and Y-shaped conjugates.
Pengju Pan et al.
Langmuir : the ACS journal of surfaces and colloids, 28(40), 14347-14356 (2012-09-28)
Linear and miktoarm star-shaped diblock copolymers consisting of single-stranded DNA and poly(N-isopropylacrylamide) (PNIPAAm) with various compositions were synthesized via atom transfer radical polymerization and click chemistry. The temperature-responsive phase transition behavior, micellization, was systematically examined using UV-vis spectrometry, high-sensitivity differential
Manuel Pernia Leal et al.
ACS nano, 6(12), 10535-10545 (2012-11-03)
We report a procedure to grow thermo-responsive polymer shells at the surface of magnetic nanocarriers made of multiple iron oxide superparamagnetic nanoparticles embedded in poly(maleic anhydride-alt-1-ocatadecene) polymer nanobeads. Depending on the comonomers and on their relative composition, tunable phase transition
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 535311-10G | 04061832565125 |