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763918

DL-α-Tocopherol methoxypolyethylene glycol succinate solution

Name: <SC>DL</SC>-&#945;-Tocopherol methoxypolyethylene glycol succinate solution
Brand: ALDRICH

5 wt. % in H2O, liquid

Synonym(s):

Polyethylene glycol, TPGS-750-M

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About This Item

Linear Formula:

(C₂H₄O)_nC₃₄H₅₆O₅

CAS Number:

1309573-60-1

MDL number:

MFCD12546177

NACRES:

NA.22

UNSPSC Code:

51171641

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Properties

Product Name

DL-α-Tocopherol methoxypolyethylene glycol succinate solution, 5 wt. % in H₂O

form

liquid

Quality Level

100

reaction suitability

reagent type: catalyst
reaction type: C-H Activation, reagent type: surfactant

IVD

for in vitro diagnostic use

greener alternative product characteristics

Catalysis
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

concentration

5 wt. % in H₂O

refractive index

n20/D 1.340

density

0.981 g/mL at 25 °C

greener alternative category

Aligned,

Description

General description

Learn More at the Professor and Product Portal of Professor Bruce Lipshutz.

We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product TPGS-750-M is a lead surfactant for many transition metal-catalyzed cross-couplings and has been enhanced for catalytic efficiency. Find details here.

Application

Nonionic amphile used to increase aqueous solubility of lipophilic catalysts and substrates. Olefin metathesis, Sonogashira, Suzuki-Miyaura, and Buchwald cross-coupling reactions have been successfully performed in aqueous media employing TPGS-750-M.

On the Way Towards Greener Transition-Metal-Catalyzed Processes as Quantified by E Factors

Second generation amphiphile which forms micelles upon dissolution in water allowing a variety of cross-coupling reactions to take place in water instead of organic solvent.

Included among the possible reactions are:

Olefin metathesis
Pd-catalyzed cross coupling reactions including Heck, Suzuki-Miyaura, Sonogashira and Buchwald-Hartwig reactions
C-H activation reactions

Second generation amphiphile for cross-coupling reactions in water

Other Notes

Watch Professor Lipshutz talk about TPGS-750-M in this webinar:
From milligrams to kilograms: synthetic chemistry following nature′s lead

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Storage Class

12 - Non Combustible Liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number

BGBC5115V

BGBC2950V

MKBL3964

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Protocols

Cross-Coupling Reactions in Water

TPGS-750-M surfactant enables various reactions in water at room temperature, enhancing efficiency and versatility in synthesis.

Articles

TPGS-750-M：用于室温下水中有机金属化学反应的第二代两亲物

Lipshutz及其同事最近开发了第二代技术，用于基于聚氧乙戊基-α-生育酚琥珀酸酯衍生物TPGS-750-M的原始PTS表面活性剂。

Lipshutz Surfactants Portfolio

Surfactants for efficient reactions in water as a green chemistry alternative.

Palladium-catalyzed Cross-coupling Reactions

A variety of palladium-catalyzed cross-coupling reactions can be run under room temperature conditions in water with TPGS- 750-M, using a variety of commercially available palladium complexes and ligands.

View All Articles

Global Trade Item Number

SKU	GTIN
763918-100ML	04061838129499
763918-10ML	04061838129505
763918-500ML	04061842293063
763918-50ML	04061838129512