808628
Gold nanoparticles
5 nm diameter, biotin terminated, PEG 5000 coated, OD 50, dispersion in H2O
Synonym(s):
Biotin Gold
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About This Item
UNSPSC Code:
12141717
NACRES:
NA.23
EC Number:
231-791-2
material
PEG 5000
Quality Level
form
dispersion in H2O, nanoparticles
packaging
pkg of 0.5 mL
OD
50
surface area
6.18 m2/g
diameter
5 nm
pH
5-7
density
1.00 g/cm3
λmax
513-517 nm
functional group
biotin
storage temp.
2-8°C
InChI
1S/Au
InChI key
PCHJSUWPFVWCPO-UHFFFAOYSA-N
General description
Gold nanoparticles PEG 5000 biotin terminated.
Application
Gold nanoparticles 5 nm diameter, biotin terminated, PEG 5000 coated, OD 50, dispersion in H2O can be used as a theranostic agent for potential usage in cancer therapy and treatment of COVID-19. It can also be used in the detection of pathogens for biosensing applications. AuNPs may be used to prepare SARS-CoV-2 conjugate for COVID-19 detection using lateral flow immunoassay technique.
Biotin functionalized gold nanoparticles are suitable for binding of streptavidin labelled conjugates. The gold nanoparticle label allows for straightforward detection of streptavidin by measuring the increase in absorbance of the sample upon binding. The absorption maximum is gold nanoparticle size dependent, and ranges from 515-520 nm for a 5 nm particle to 572 nm for a 100 nm particle.
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Storage Class
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
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Articles
Professors summarize recent 2D materials synthesis advancements and biosensing applications in various fields.
Motao Zhu et al.
ACS nano, 14(3), 3703-3717 (2020-02-15)
Engineered nanoparticles could trigger inflammatory responses and potentiate a desired innate immune response for efficient immunotherapy. Here we report size-dependent activation of innate immune signaling pathways by gold (Au) nanoparticles. The ultrasmall-size (<10 nm) Au nanoparticles preferentially activate the NLRP3
Gold nanoparticles surface-functionalized with paclitaxel drug and biotin receptor as theranostic agents for cancer therapy
Heo DN, et al.
Biomaterials, 33(3), 856-866 (2012)
Optimizing use of theranostic nanoparticles as a life-saving strategy for treating COVID-19 patients
Itani R, et al.
Theranostics, 10(13), 5932-5932 (2020)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 808628-0.5ML | 04061832995465 |