G6503
Glycine ethyl ester hydrochloride
99%, for peptide synthesis
Synonym(s):
GEE, Ethyl glycinate hydrochloride
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About This Item
Linear Formula:
NH2CH2COOC2H5 · HCl
CAS Number:
Molecular Weight:
139.58
NACRES:
NA.22
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
EC Number:
210-787-4
MDL number:
Beilstein/REAXYS Number:
3594034
Product Name
Glycine ethyl ester hydrochloride, 99%
Quality Level
assay
99%
form
powder or chunks
reaction suitability
reaction type: solution phase peptide synthesis
technique(s)
drug transporter assay: suitable
color
white
mp
145-146 °C (lit.)
application(s)
peptide synthesis
SMILES string
Cl.CCOC(=O)CN
InChI
1S/C4H9NO2.ClH/c1-2-7-4(6)3-5;/h2-3,5H2,1H3;1H
InChI key
TXTWXQXDMWILOF-UHFFFAOYSA-N
Application
Glycine ethyl ester (GEE) is used in conjunction with N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide (EDC) for carboxyl-footprinting studies of proteins. The GEE/EDC protocol effects specific derivatization of glutamate and aspartate carboxyl side chains on intact proteins. This reaction is readily done under aqueous conditions at physiological pH.
signalword
Danger
hcodes
Hazard Classifications
Eye Dam. 1
Storage Class
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Zhang, H.; et al.
Molecular and Cellular Proteomics, 10 (2011)
Hao Zhang et al.
International journal of mass spectrometry, 312, 78-86 (2012-03-13)
Protein structure determines function in biology, and a variety of approaches have been employed to obtain structural information about proteins. Mass spectrometry-based protein footprinting is one fast-growing approach. One labeling-based footprinting approach is the use of a water-soluble carbodiimide, 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide
Michael N Okal et al.
Malaria journal, 14, 250-250 (2015-06-20)
Choice egg-count bioassays are a popular tool for analysing oviposition substrate preferences of gravid mosquitoes. This study aimed at improving the design of two-choice experiments for measuring oviposition substrates preferences of the malaria vector Anopheles gambiae senso lato, a mosquito
Global Trade Item Number
| SKU | GTIN |
|---|---|
| G6503-500G-A | 04061833639245 |
| G6503-100G-A | 04061838354617 |
| G6503-1G | 04061826059524 |
| G6503-5G | 04061833639252 |
| G6503-5G-A | 04061833639269 |