QCRBNSET
QuicTPD™ CRBN ligand Set
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About This Item
NACRES:
NA.21
packaging
pkg of 50 mg
Quality Level
sustainability
Greener Alternative Product
greener alternative category
storage temp.
2-8°C
General description
5-Amino Thalidomide, Lenalidomide, Pomalidomide and C-5 Lenalidomide are recruiters of CRBN protein that can be leveraged for targeted protein degradation research. They are provided at 50 mg each.
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Application
Useful for construction of CRBN based partial protacs of full protacs, by utilizing the amine terminus to add suitable linkers with peptide coupling reactions. These can also be used as controls/competitors to confirm target engagement of putative protacs.
Features and Benefits
Quantities provided are sufficient to do at least 96 reactions at 2 micromole each with a D2B approach with a library of suitable bifunctional linkers ending in carboxylic acid terminus to generate a library of partial protacs or full protacs.
Other Notes
CRBN Ligand Set part of QuicTPD™ kit
Legal Information
QuicTPD is a trademark of Merck KGaA, Darmstadt, Germany
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Acute Tox. 4 Dermal - Repr. 1A - STOT RE 2
target_organs
Blood
Storage Class
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
Regulatory Information
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Global Trade Item Number
| SKU | GTIN |
|---|---|
| QCRBNSET-1KT | 04065272377317 |