assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 g (131601P-1g), pkg of 10 × 1 g (131601P-10g), pkg of 5 × 1 g (131601P-5g)
manufacturer/tradename
Avanti Research™ - A Croda Brand
lipid type
phospholipids
phosphoglycerides
shipped in
dry ice
storage temp.
−20°C
SMILES string
[P](=O)([O-])(OC[C@H](OC(=O)CCCCCCC\C=C/CCCCCCCC)COC(=O)CCCCCCCCCCCCCCC)OCC[N+](C)(C)C
InChI
1S/C42H82NO8P/c1-6-8-10-12-14-16-18-20-21-23-25-27-29-31-33-35-42(45)51-40(39-50-52(46,47)49-37-36-43(3,4)5)38-48-41(44)34-32-30-28-26-24-22-19-17-15-13-11-9-7-2/h20-21,40H,6-19,22-39H2,1-5H3/b21-20-/t40-/m1/s1
InChI key
WTJKGGKOPKCXLL-VYOBOKEXSA-N
General description
l-α-phosphatidylcholine constitutes 20% of the total phospholipids in chicken egg. It has palmitic acid (16:0) and oleic acid (18:1) in at sn-1 and sn-2 positions, respectively.
Egg PC (95%) is a mixture of 16 to 22 carbon atoms long acyl chain containing multiple double bonds. Major portion (98%) of phospholipid contains a single saturated and unsaturated chain.
Egg PC is a further purification of Total Egg Extract. This Natural Lipid is a mixture, and the structure shown above is only representative of one possible structure present in the product. Refer to chart for average fatty acid distribution.
Application
Egg PC (95%) has been used for the reconstitution of purified Kv1.3 into liposomes.
Egg PC (95%) has been used in the synthesis of high-density lipoprotein (HDL) based nanoparticle for nerve growth factor (NGF) encapsulation. It has also been used in the proteoliposome preparation.
Biochem/physiol Actions
Egg PC in its saturated form favors inhibition of cholesterol absorption. It is used in lipid preparation and liposomes for biophysical studies. Egg PC contributes cardiovascular disease (CVD) risk by acting as a substrate for microbes leading to of trimethylamine N-oxide (TMAO) synthesis.
Packaging
125 mL Amber Wide Mouth Screw Cap Glass Bottle (131601P-5g)
250 mL Amber Wide Mouth Screw Cap Glass Bottle (131601P-10g)
60 mL Amber Wide Mouth Screw Cap Glass Bottle (131601P-1g)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
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Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Structure of Outward-Facing PglK and Molecular Dynamics of Lipid-Linked Oligosaccharide Recognition and Translocation
Perez C, et al.
Structure (2019)
Preparation and characterization of novel hdl-mimicking nanoparticles for nerve growth factor encapsulation
Zhu, Jing and Dong, Xiaowei
Journal of Visualized Experiments, (123), e55584-e55584 (2008)
A multiplatform strategy for the discovery of conventional monoclonal antibodies that inhibit the voltage-gated potassium channel Kv1. 3
Bednenko J, et al.
MAbs, 10(4), 636-650 (2018)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 131601P-10G | 04061835353255 |
| 131601P-1G | 04061835353262 |
| 131601P-5G | 04061835353279 |