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About This Item
Empirical Formula (Hill Notation):
C30H52O
CAS Number:
Molecular Weight:
428.73
UNSPSC Code:
12352211
NACRES:
NA.25
description
24,25-dihydrolanosterol
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 mg (700067P-1mg), pkg of 1 × 5 mg (700067P-5mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand
shipped in
dry ice
storage temp.
−20°C
SMILES string
C[C@]12CCC([C@](CC[C@H](O)C3(C)C)(C)C3CC4)=C4[C@]1(C)CC[C@]2([H])[C@]([H])(C)CCCC(C)C
InChI
1S/C30H52O/c1-20(2)10-9-11-21(3)22-14-18-30(8)24-12-13-25-27(4,5)26(31)16-17-28(25,6)23(24)15-19-29(22,30)7/h20-22,25-26,31H,9-19H2,1-8H3/t21-,22-,25?,26+,28-,29-,30+/m1/s1
InChI key
MBZYKEVPFYHDOH-XCEBNUDKSA-N
General description
Dihydrolanosterol is a natural sterol.
Application
Dihydrolanosterol has been used to induce degradation of 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGCR).
Packaging
5 mL Amber Glass Screw Cap Vial (700067P-1mg)
5 mL Amber Glass Screw Cap Vial (700067P-5mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
No data available
flash_point_c
No data available
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Discovery of a potent HMG-CoA reductase degrader that eliminates statin-induced reductase accumulation and lowers cholesterol
Jiang SY, et al.
Nature Communications, 9(1), 5138-5138 (2018)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 700067P-1MG | 04061835384778 |
| 700067P-5MG | 04061835384785 |