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700126P

Avanti

campesterol

Avanti Research™ - A Croda Brand

Synonym(s):

campest-5-en-3β-ol

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About This Item

Empirical Formula (Hill Notation):
C28H48O
CAS Number:
474-62-4
Molecular Weight:
400.68
MDL number:
MFCD00670159
UNSPSC Code:
12352211
NACRES:
NA.25
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Product Name

campesterol, Avanti Research™ - A Croda Brand 700126P, powder

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 mg (700126P-1mg), pkg of 1 × 10 mg (700126P-10mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 700126P

shipped in

dry ice

storage temp.

−20°C

SMILES string

OC1CCC2(C3C(C4C(C(CC4)C(CCC(C(C)C)C)C)(CC3)C)CC=C2C1)C

InChI

1S/C28H48O/c1-18(2)19(3)7-8-20(4)24-11-12-25-23-10-9-21-17-22(29)13-15-27(21,5)26(23)14-16-28(24,25)6/h9,18-20,22-26,29H,7-8,10-17H2,1-6H3

InChI key

SGNBVLSWZMBQTH-UHFFFAOYSA-N

General description

Campesterol is a plant sterol, which is an analog of cholesterol and a brassinosteroid (BR) precursor. The enzyme diminute/dwarf1 mediates the synthesis of campesterol from 24-methylenecholesterol. Campesterol possesses methyl group at C-24 position of the side chain in the cholesterol structure.

Application

Campesterol may be used as a plant sterol to test its effect on the transcriptional activation of liver X receptor α (LXRA) in breast cancer cells. It may also be used as a sterol standard for calibration curve generation in liquid chromatography multiple reaction monitoring (LC-MRM) analysis.

Biochem/physiol Actions

Campesterol reduces the levels of chylomicron, low-density lipoprotein (LDL) and very low-density lipoprotein (VLDL)-apoB100. A high ratio of campesterol to sitosterol enhances fiber elongation in cotton fibres.

Packaging

5 mL Amber Glass Screw Cap Vial (700126P-10mg)
5 mL Amber Glass Screw Cap Vial (700126P-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

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pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Samantha A Hutchinson et al.
International journal of molecular sciences, 20(13) (2019-07-05)
Low fruit and vegetable consumption and high saturated fat consumption causes elevated circulating cholesterol and are breast cancer risk factors. During cholesterol metabolism, oxysterols form that bind and activate the liver X receptors (LXRs). Oxysterols halt breast cancer cell proliferation

Global Trade Item Number

SKUGTIN
700126P-10MG04061835383863
700126P-1MG04061835383870