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About This Item
Empirical Formula (Hill Notation):
C40H77NO10PNa
CAS Number:
Molecular Weight:
786.00
NACRES:
NA.25
UNSPSC Code:
51191904
description
1,2-diheptadecanoyl-sn-glycero-3-phospho-L-serine (sodium salt)
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 10 mg (840028P-10mg), pkg of 1 × 25 mg (840028P-25mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand
lipid type
cardiolipins
phospholipids
shipped in
dry ice
storage temp.
−20°C
SMILES string
[H][C@@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)(OC(CCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCC)=O.[Na+]
InChI
1S/C40H78NO10P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-38(42)48-33-36(34-49-52(46,47)50-35-37(41)40(44)45)51-39(43)32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h36-37H,3-35,41H2,1-2H3,(H,44,45)(H,46,47);/q;+1/p-1/t36-,37+;/m1./s1
InChI key
HNPCQASYRKKJRQ-JBEIVTSCSA-M
General description
Phosphatidylserine (PtdSer) is an anionic phospholipid abundantly present in the eukaryotic cell. 10% of the total cellular lipid consists of phosphatidylserine. O‐phospho‐L‐serine is a heat‐stable substrate.
Application
17:0 PS has been used as an internal standard for BXD liver and plasma sample analysis. It may be used as a standard to estimate the cellular lipidome of Saccharomyces cerevisiae by liquid chromatography coupled with tandem mass spectrometry.
Biochem/physiol Actions
Phosphatidylserine (PtdSer) participates in various intracellular signaling pathways. It also play a major role in apoptosis and blood clotting.
Packaging
5 mL Amber Glass Screw Cap Vial (840028P-10mg)
5 mL Amber Glass Screw Cap Vial (840028P-25mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class
11 - Combustible Solids
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Koshiki Mino et al.
FEBS letters, 551(1-3), 133-138 (2003-09-11)
O-Acetylserine sulfhydrylase (OASS), a pyridoxal 5'-phosphate (PLP)-dependent enzyme, catalyzes the synthesis of L-cysteine from O-acetyl-L-serine and sulfide. O-Acetyl-L-serine is labile at high temperatures at which hyperthermophilic archaea live. Herein, a study of the substrate specificity of OASS from Aeropyrum pernix
Emily L Gill et al.
Journal of proteome research, 19(1), 424-431 (2019-11-13)
Parkinson's disease (PD) is characterized by the loss of dopaminergic neurons in the substantia nigra pars compacta of the brain, as well as the degeneration of motor and nonmotor circuitries. The cause of neuronal death is currently unknown, although chronic
Rose M Gathungu et al.
Analytical chemistry, 90(22), 13523-13532 (2018-09-29)
Lipidomics requires the accurate annotation of lipids in complex samples to enable determination of their biological relevance. We demonstrate that unintentional in-source fragmentation (ISF, common in lipidomics) generates ions that have identical masses to other lipids. Lysophosphatidylcholines (LPC), for example
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 840028P-10MG | 04061835228485 |
| 840028P-25MG | 04061835228492 |