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About This Item
Empirical Formula (Hill Notation):
C41H80NO8P
CAS Number:
Molecular Weight:
746.05
UNSPSC Code:
51191904
NACRES:
NA.25
Product Name
18:0-18:1 PE, 1-stearoyl-2-oleoyl-sn-glycero-3-phosphoethanolamine, powder
assay
>99% (TLC)
form
powder
packaging
pkg of 2 × 100 mg (850758P-200mg), pkg of 1 × 25 mg (850758P-25mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 850758P
lipid type
cardiolipins
phospholipids
shipped in
dry ice
storage temp.
−20°C
SMILES string
[H][C@@](COP([O-])(OCC[NH3+])=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O
InChI
1S/C21H14Cl2N2O2/c1-12-8-9-18-17(10-12)25-21(27-18)13-4-2-5-14(11-13)24-20(26)15-6-3-7-16(22)19(15)23/h2-11H,1H3,(H,24,26)
InChI key
GKFNHDBVWFEZCJ-UHFFFAOYSA-N
General description
Phosphatidylethanolamine (PE) is a glycerophospholipid.
Application
1-stearoyl-2-oleoyl-sn-glycero-3-phosphoethanolamine (18:0-18:1 PE) may be used:
- as a component in monomolecular films domain formation and characterization
- in the synthesis of mixed acyl chain 7-nitrobenz-2-oxa-1,3-diazol-4-yl-diacyl-sn-glycero-3-phosphoethanolamine (N-NBD-PE) and (N-lissamine rhodamine B sulfonyl)-diacyl-sn-glycero-3-phosphoethanolamine (N-Rh-PE) probes
- in the preparation of liposomes
Biochem/physiol Actions
Phosphatidylethanolamine (PE) serves as a lipid chaperon. It is known to participate in the initiation of autophagy.
Packaging
5 mL Clear Glass Sealed Ampule (850758P-200mg)
5 mL Clear Glass Sealed Ampule (850758P-25mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
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Storage Class
11 - Combustible Solids
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Detection of lipid domains in docasahexaenoic acid-rich bilayers by acyl chain-specific FRET probes.
W Stillwell et al.
Chemistry and physics of lipids, 104(2), 113-132 (2000-02-11)
A major problem in defining biological membrane structure is deducing the nature and even existence of lipid microdomains. Lipid microdomains have been defined operationally as heterogeneities in the behavior of fluorescent membrane probes, particularly the fluorescence resonance energy transfer (FRET)
Federica Gibellini et al.
IUBMB life, 62(6), 414-428 (2010-05-27)
The glycerophospholipids phosphatidylcholine (PC) and phosphatidylethanolamine (PE) account for greater than 50% of the total phospholipid species in eukaryotic membranes and thus play major roles in the structure and function of those membranes. In most eukaryotic cells, PC and PE
Dhaval Patel et al.
Oxidative medicine and cellular longevity, 2017, 4829180-4829180 (2017-08-09)
Phosphatidylethanolamine (PE) is the second most abundant phospholipid in mammalian cells. PE comprises about 15-25% of the total lipid in mammalian cells; it is enriched in the inner leaflet of membranes, and it is especially abundant in the inner mitochondrial
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 850758P-25MG | 04061835231331 |
| 850758P-200MG | 04061835231324 |