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About This Item
Empirical Formula (Hill Notation):
C33H58 D7NO3
CAS Number:
Molecular Weight:
530.92
MDL number:
UNSPSC Code:
12352100
NACRES:
NA.25
Assay:
>99% (TLC)
Form:
powder
Product Name
C15 Ceramide-d7 (d18:1-d7/15:0), Avanti Research™ - A Croda Brand 860681P, powder
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 mg (860681P-1mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 860681P
shipped in
dry ice
storage temp.
−20°C
SMILES string
OC[C@]([H])(NC(CCCCCCCCCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCC([2H])([2H])C([2H])([2H])C([2H])([2H])[2H]
InChI key
HBULQAPKKLNTLT-CVNQHAACSA-N
General description
C15 Ceramide (d18:1/15:0) is a synthetic ceramide containing sphingosine with pentadecanoic acid. C15 Ceramide-d7 (d18:1-d7/15:0) is a deuterated derivative of C15 Ceramide (d18:1/15:0).
Application
C15 Ceramide-d7 (d18:1-d7/15:0) has been used as a standard to measure C32–C34 ceramides in zebrafish brain and human embryonic kidney cell line (HEK293) by thermo q-exactive plus quadrupole-orbitrap mass spectrometery. It has also been used to measure the concentration of sphingolipids in right submandibular glands of mice by ultra-high-performance liquid chromatography-tandem mass spectrometry (UHPLC/MS/MS).
Biochem/physiol Actions
Ceramides serve as precursors for several sphingolipids. Ceramides play a significant role in cell differentiation, proliferation, and apoptosis. In addition, they also acts as secondary transmitters in cell signaling.
Packaging
5 mL Amber Glass Screw Cap Vial (860681P-1mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
No data available
flash_point_c
No data available
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Claude Vieu et al.
Journal of lipid research, 43(3), 510-522 (2002-03-15)
This study reports a single-step analysis of the molecular species of endogenous ceramides and of the ceramide moiety of sphingomyelins in biological samples, using gas liquid chromatography (GLC). Silylated sphingomyelins were quantitatively converted to monosilylated ceramide upon injection into GLC
Tejia Zhang et al.
Scientific reports, 9(1), 19939-19939 (2019-12-29)
Extensive characterisations of the zebrafish genome and proteome have established a foundation for the use of the zebrafish as a model organism; however, characterisation of the zebrafish lipidome has not been as comprehensive. In an effort to expand current knowledge
Hady Razak Hady et al.
Journal of clinical medicine, 8(12) (2019-12-18)
The liver plays a central role in the glucose and lipid metabolism. Studies performed on animal models have shown an important role of lipid accumulation in the induction of insulin resistance. We sought to explain whether in obese humans, the
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 860681P-1MG | 04061835191857 |