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880150P

Avanti

14:0 PEG2000 PE

Avanti Research™ - A Croda Brand

Synonym(s):

1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] (ammonium salt)

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About This Item

CAS Number:
474922-82-2
UNSPSC Code:
12352211
NACRES:
NA.25
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Product Name

14:0 PEG2000 PE, Avanti Research™ - A Croda Brand 880150P, powder

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 g (880150P-1g), pkg of 1 × 200 mg (880150P-200mg), pkg of 1 × 25 mg (880150P-25mg), pkg of 1 × 500 mg (880150P-500mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 880150P

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCCNC(OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)=O)=O)(OC(CCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCC)=O.[NH4+]

InChI

1S/C125H248NO55P.H3N/c1-4-6-8-10-12-14-16-18-20-22-24-26-123(127)178-120-122(181-124(128)27-25-23-21-19-17-15-13-11-9-7-5-2)121-180-182(130,131)179-29-28-126-125(129)177-119-118-176-117-116-175-115-114-174-113-112-173-111-110-172-109-108-171-107-106-170-1

InChI key

QQHAAYKTQQJGGW-YMNXLSEASA-N

General description

14:0 PEG2000 PE, also called as 1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] (DMPE-PEG2000), is a polyethylene glycol (PEG)-phospholipid conjugate. It belongs to a group of polymerizable lipids. Incorporation of DMPE-PEG in the vesicle formulation stops aggregation of vesicles upon peptide addition.

Application

14:0 PEG2000 PE or 1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] has been used in: giant vesicles preparation, lipid nanoparticle (LNP) formulation, unilamellar liposomes preparation for small-angle X-ray scattering (SAXS) experiments

Packaging

20 mL Clear Glass Screw Cap Vial (880150P-1g)
20 mL Clear Glass Screw Cap Vial (880150P-500mg)
5 mL Amber Glass Screw Cap Vial (880150P-200mg)
5 mL Amber Glass Screw Cap Vial (880150P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class

11 - Combustible Solids

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Josefine Eilsø Nielsen et al.
Biochimica et biophysica acta. Biomembranes, 1861(7), 1355-1364 (2019-04-13)
The naturally occurring peptide indolicidin from bovine neutrophils exhibits strong biological activity against a broad spectrum of microorganisms. This is believed to arise from selective interactions with the negatively charged cytoplasmic lipid membrane found in bacteria. We have investigated the
Dominique Leboeuf et al.
Molecular therapy : the journal of the American Society of Gene Therapy, 28(4), 1092-1104 (2020-02-24)
The N-degron pathway is an emerging target for anti-tumor therapies, because of its capacity to positively regulate many hallmarks of cancer, including angiogenesis, cell proliferation, motility, and survival. Thus, inhibition of the N-degron pathway offers the potential to be a
Abdullah Lone et al.
Molecules (Basel, Switzerland), 24(24) (2019-12-19)
The increasing emergence of multi-drug resistant bacteria is a serious threat to public health worldwide. Antimicrobial peptides have attracted attention as potential antibiotics since they are present in all multicellular organisms and act as a first line of defence against

Global Trade Item Number

SKUGTIN
880150P-200MG04061835187751
880150P-500MG04061835187775
880150P-1G04061835187744
880150P-25MG04061835187768