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Merck
CN

LM1000

Avanti

12:0-13:0 PC

Avanti Research - A Croda Brand

Synonym(s):

1-dodecanoyl-2-tridecanoyl-sn-glycero-3-phosphocholine

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About This Item

Empirical Formula (Hill Notation):
C33H66NO8P
CAS Number:
Molecular Weight:
635.85
UNSPSC Code:
12352211
NACRES:
NA.25
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Product Name

12:0-13:0 PC, Avanti Research - A Croda Brand LM1000, methanol solution

assay

>99% (TLC)

form

methanol solution

packaging

pkg of 1 × 1 mL (LM1000-1EA)

manufacturer/tradename

Avanti Research - A Croda Brand LM1000

concentration

~10 μg/mL (Refer to C of A for lot specific concentration.)

shipped in

dry ice

storage temp.

−20°C

SMILES string

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCCCCC)=O)COC(CCCCCCCCCCC)=O)=O

InChI key

FCTBVSCBBWKZML-WJOKGBTCSA-N

General description

Phospholipids are major structural biomolecules found in biological membranes. Phosphocholine (PC) is an intermediate of phosphatidylcholine synthesis catalyzed by choline kinase.

Application

12:0-13:0 PC or 1-dodecanoyl-2-tridecanoyl-sn-glycero-3-phosphocholine has been used:
  • as an internal standard in liquid chromatography/mass spectrometry (LC/MS) analysis
  • as a lipid standard for phospholipid quantification by MS
  • as an internal standard for the retention time recalibration during LC-MS data processing
  • as an MS grade lipid standard for lipid extraction from macrophages

Biochem/physiol Actions

Phospholipids participate in protein mediated intracellular and extracellular signaling processes.

Packaging

2 mL Amber Glass Sealed Ampule (LM1000-1EA)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Disclaimer

Supply conditions do not apply to the regions and states of Brazil: North, Northeast, Mato Grosso do Sul, Mato Grosso, and Rio Grande do Sul.


signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes

Storage Class

3 - Flammable liquids

wgk

WGK 2

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup

Regulatory Information

危险化学品

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Akifumi Shiomi et al.
Bioscience, biotechnology, and biochemistry, 84(3), 583-593 (2019-11-26)
Fish cell lines are widely used for the studies of developmental biology, virology, biology of aging, and nutrition physiology. However, little is known about their physicochemical properties. Here, we report the phospholipid compositions and mechanical properties of cell membranes derived
Shayne A Snider et al.
The Journal of biological chemistry, 293(29), 11600-11611 (2018-06-09)
Choline is an essential nutrient that is required for synthesis of the main eukaryote phospholipid, phosphatidylcholine. Macrophages are innate immune cells that survey and respond to danger and damage signals. Although it is well-known that energy metabolism can dictate macrophage
Penelope Dimas et al.
eLife, 8 (2019-05-08)
Oligodendrocytes (OLs) support neurons and signal transmission in the central nervous system (CNS) by enwrapping axons with myelin, a lipid-rich membrane structure. We addressed the significance of fatty acid (FA) synthesis in OLs by depleting FA synthase (FASN) from OL



Global Trade Item Number

SKUGTIN
LM1000-1EA04061837669569