Skip to Content
Merck
CN

Key Documents

View All Documentation

B-023

BSTFA

with 1% TMCS, kit of 10 × 1 mL, analytical standard, Cerilliant®

Synonym(s):

N,O-Bis(trimethylsilyl)trifluoroacetamide, BSTFA

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View

About This Item

Linear Formula:
CF3C[=NSi(CH3)3]OSi(CH3)3
CAS Number:
25561-30-2
Molecular Weight:
257.40
UNSPSC Code:
41116107
PubChem Substance ID:
329773102
NACRES:
NA.24
Beilstein/REAXYS Number:
2050024
MDL number:
MFCD00008269
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

BSTFA (with 1% TMCS), kit of 10 × 1 mL, analytical standard, Cerilliant®

grade

analytical standard

Quality Level

100

reaction suitability

reagent type: derivatization reagent
reaction type: Acylations

packaging

kit of 10 × 1 mL

manufacturer/tradename

Cerilliant®

technique(s)

gas chromatography (GC): suitable

refractive index

n20/D 1.384 (lit.)

bp

45-50 °C/14 mmHg (lit.)

density

0.969 g/mL at 25 °C (lit.)

application(s)

forensics and toxicology

format

neat

storage temp.

−20°C

SMILES string

C[Si](C)(C)O\C(=N\[Si](C)(C)C)C(F)(F)F

InChI

1S/C8H18F3NOSi2/c1-14(2,3)12-7(8(9,10)11)13-15(4,5)6/h1-6H3/b12-7+

InChI key

XCOBLONWWXQEBS-KPKJPENVSA-N

Application

BSTFA (with 1% TMCS) may be used as a derivatizing agent in the following:
  • Analysis of estrogenic compounds in water samples using gas chromatography coupled to mass spectrometry (GC-MS).
  • Quantification of α-pyrrolidinovalerophenone (α-PVP) and its metabolites in urine samples using gas chromatography coupled to mass spectrometry (GC-MS).

Features and Benefits

  • BSTFA is very versatile, reacting with a range of polar organic compounds and replacing active hydrogens with a −Si(CH3)3 (trimethylsilyl) group.
  • Reacts rapidly and more completely than BSA.;
  • TMCS increases the reactivity of BSTFA (or other silylation reagents).
  • Amides and many secondary amines and hindered hydroxyls, incompletely derivatized by BSTFA alone, can be derivatized by adding 1-20% TMCS to BSTFA.
  • Has good solvent properties and can function as a silylation reagent without additional solvents.
  • Alternatively, the mixture is very soluble in most commonly used silylation solvents.

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Still not finding the right product?

Explore all of our products under BSTFA (with 1% TMCS)

pictograms

FlameExclamation mark
GHS02,GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2

Storage Class

3 - Flammable liquids

wgk

WGK 3

flash_point_f

75.2 °F - closed cup

flash_point_c

24.0 °C - closed cup

Regulatory Information

危险化学品

This item has

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Optimisation of derivatisation for the analysis of estrogenic compounds in water by solid-phase extraction gas chromatography--mass spectrometry
Zhang LZ, et al.
Analytica Chimica Acta, 577(1), 52-61 (2006)
Determination of synthetic cathinone $\alpha$-pyrrolidinovalero-phenone and its metabolite in urine using solid-phase extraction and gas chromatography--mass spectrometry
Cheng WK, et al.
Rapid Communications in Mass Spectrometry, 34(1), e8579-e8579 (2020)

Global Trade Item Number

SKUGTIN
B-023-10X1ML04061837811951