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H-107

1,25-Dihydroxyvitamin D3-13C3 (25,26,27-13C3) solution

5 μg/mL in ethanol, ampule of 1 mL, certified reference material, Cerilliant®

Synonym(s):

Deuterated 1

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About This Item

Empirical Formula (Hill Notation):
13C3C24H44O3
Molecular Weight:
419.61
NACRES:
NA.24
UNSPSC Code:
41116107
EC Number:
200-578-6
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grade

certified reference material

Quality Level

300

form

liquid

feature

(Snap-N-Spike®)

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

5 μg/mL in ethanol

mp

-143.99 °C

application(s)

clinical testing

format

single component solution

storage temp.

−70°C

SMILES string

O[C@@H](C[C@H](O)C/1=C)CC1=C\C=C2[C@@](CC[C@]3([H])[C@H](C)CCC[13C](O)([13CH3])[13CH3])([H])[C@]3(C)CCC\2

InChI

1S/C27H44O3/c1-18(8-6-14-26(3,4)30)23-12-13-24-20(9-7-15-27(23,24)5)10-11-21-16-22(28)17-25(29)19(21)2/h10-11,18,22-25,28-30H,2,6-9,12-17H2,1,3-5H3/b20-10+,21-11-/t18-,22-,23-,24+,25+,27-/m1/s1/i3+1,4+1,26+1

InChI key

GMRQFYUYWCNGIN-SYUIRNBGSA-N

General description

A stable-labeled internal standard suitable for quantitation of 1,25-Dihydroxyvitamin D3 levels by LC-MS/MS. 1,25-Dihydroxyvitamin D3, also known as calcitriol, is a hormonally active metabolite of vitamin D responsible for regulating calcium. Measurement of 1,25-Dihydroxyvitamin D3 is used to distinguish some cases of primary hyperparathyroidism from hypercalcemia of cancer and for the differential diagnosis of vitamin D-dependent rickets.

Other Notes

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

FlameExclamation mark
GHS02,GHS07

signalword

Danger

hcodes

H225,H319

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 2

Storage Class

3 - Flammable liquids

wgk

WGK 1

flash_point_f

57.2 °F - closed cup

flash_point_c

14.0 °C - closed cup

Regulatory Information

危险化学品

This item has

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Mark A Crumling et al.
PloS one, 7(12), e53280-e53280 (2013-01-04)
Cyclodextrins are sugar compounds that are increasingly finding medicinal uses due to their ability to complex with hydrophobic molecules. One cyclodextrin in particular, 2-hydroxypropyl-β-cyclodextrin (HPβCD), is used as a carrier to solubilize lipophilic drugs and is itself being considered as
Fang Liu et al.
Proceedings of the National Academy of Sciences of the United States of America, 116(26), 12986-12995 (2019-06-12)
The aberrant hedgehog (Hh) pathway plays important roles in multiple cancer types, therefore serving as a promising drug target. Current clinically available hedgehog-targeted drugs act mostly by antagonizing the upstream component smoothened; however, both primary and acquired resistance to FDA-approved
Matthew B Pomrenze et al.
Cell reports, 29(1), 13-21 (2019-10-03)
Central amygdala (CeA) neurons that produce corticotropin-releasing factor (CRF) regulate anxiety and fear learning. These CeACRF neurons release GABA and several neuropeptides predicted to play important yet opposing roles in these behaviors. We dissected the relative roles of GABA, CRF
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Global Trade Item Number

SKUGTIN
H-107-1ML04061833662304
Z114014-144EA04061832325828
Z114014-12EA04061832325811