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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
E11D7, monoclonal
Application:
ELISA, IHC
Citations:
4
biological source
mouse
Quality Level
conjugate
unconjugated
antibody form
purified antibody
antibody product type
primary antibodies
clone
E11D7, monoclonal
species reactivity
human
species reactivity (predicted by homology)
rat, mouse
packaging
antibody small pack of 25 μg
technique(s)
ELISA: suitable, immunohistochemistry: suitable (paraffin)
isotype
IgG1κ
NCBI accession no.
UniProt accession no.
shipped in
ambient
target post-translational modification
unmodified
Gene Information
human ... INS(3630)
mouse ... Ins1(16333)
rat ... Ins1(24505)
General description
6 kDa
Insulin is a polypeptide hormone that regulates carbohydrate metabolism. Apart from being the primary agent in carbohydrate homeostasis, it has effects on fat metabolism.
Immunogen
Epitope: Insulin
Human recombinant Insulin
Application
Anti-Insulin Antibody, clone E11D7 detects level of Insulin & has been published & validated for use in ELISA, IH(P).
ELISA (Direct) Analysis:
Insulin-coated plate was incubated with Anti-Insulin, clone E11D7 in 2-fold serial dilutions diluted in PBST from 5 μg/mL to 0.01 μg/mL.
Insulin-coated plate was incubated with Anti-Insulin, clone E11D7 in 2-fold serial dilutions diluted in PBST from 5 μg/mL to 0.01 μg/mL.
Research Category
Signaling
Metabolism
Signaling
Metabolism
Research Sub Category
Insulin/Energy Signaling
Glucose/Glycogen Metabolism
Metabolic Hormones & Receptors
Insulin/Energy Signaling
Glucose/Glycogen Metabolism
Metabolic Hormones & Receptors
Biochem/physiol Actions
Recognizes insulin
Physical form
Format: Purified
Protein G Purified
Purified mouse monolconal IgG1κ in 0.1M Tris-Glycine (pH7.4), 150mM NaCl with 0.05%NaN3
Preparation Note
Stable for 1 year at 2-8ºC from date of receipt.
Analysis Note
Immunohistochemistry Analysis:
20 μg/mL of this antibody detected insulin in β cells.
20 μg/mL of this antibody detected insulin in β cells.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Activation of PPAR? up-regulates the expression of insulin gene transcription factor MafA and ameliorates glucose-induced insulin secretion impaired by palmitate.
Mingming Cao,Yang Long,Yuzhen Tong,Jun Wan,Nanwei Tong
Molecular and Cellular Biochemistry null
Gabriel Cao et al.
PloS one, 16(6), e0243340-e0243340 (2021-06-12)
The objective of this work was to analyze the structural changes of the pancreatic islets in rats, after 6 month consuming regular and light cola for 6 months. Also, we have analyzed the possible role of PDX-1 in that process.
Mi Ran Choi et al.
Journal of ginseng research, 41(4), 503-512 (2017-10-13)
Chronic heavy alcohol consumption may raise the risk of developing type 2 diabetes mellitus. Saponins inhibit apoptosis of pancreatic islet cells and reduce lipid parameters. The present study was designed to investigate the effect of saponin on chronic ethanol-treated diabetic
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 05-1066-25UG | 04054839337710 |