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1.01900

Dimethyl sulfoxide

Name: Dimethyl sulfoxide
Brand: MM

for headspace gas chromatography SupraSolv^®

Synonym(s):

Methanesulfinylmethane, Methyl sulfoxide, Dimethyl(oxido)sulfur, DMSO, DMSO

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About This Item

Linear Formula:

(CH₃)₂SO

CAS Number:

67-68-5

Molecular Weight:

78.13

UNSPSC Code:

12191502

NACRES:

NA.03

EC Index Number:

200-664-3

MDL number:

MFCD00002089

Beilstein/REAXYS Number:

506008

Assay:

≥99.8% (GC)

Technique(s):

GC-HS: suitable

Bp:

189 °C (lit.)

Vapor pressure:

0.42 mmHg ( 20 °C)

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Properties

Quality Level

100

agency

according to Ph. Eur., according to USP

vapor density

2.7 (vs air)

vapor pressure

0.42 mmHg ( 20 °C)

product line

SupraSolv^®

assay

≥99.8% (GC)

form

liquid

autoignition temp.

573 °F

potency

28300 mg/kg LD₅₀, oral (Rat), 40000 mg/kg LD₅₀, skin (Rat)

expl. lim.

42 %, 63 °F

technique(s)

GC-HS: suitable

impurities

≤0.05% Water

evapn. residue

≤3.0 mg/L

color

APHA: ≤10

refractive index

n20/D 1.479 (lit.)

kinematic viscosity

2.14 cSt

bp

189 °C (lit.)

mp

16-19 °C (lit.)

transition temp

flash point 87 °C

density

1.10 g/mL (lit.)

storage temp.

2-30°C

SMILES string

CS(C)=O

InChI

1S/C2H6OS/c1-4(2)3/h1-2H3

InChI key

IAZDPXIOMUYVGZ-UHFFFAOYSA-N

Description

General description

SupraSolv solvents for headspace gas chromatography are developed particularly for the analysis of residual
solvents in drug substances, excipients and drug products according to ICH, Ph Eur and USP - SupraSolv headspace solvents are tested for all
residual solvents defined by the ICH.

Application

DMSO can be used as an effective solvent for dissolving a wide range of polar and non-polar compounds for sample preparation in HS-GC. Its high polarity allows for the extraction of volatile organic compounds (VOCs) from complex matrices, such as biological samples or environmental matrices. DMSO also enhances the volatility of certain compounds, facilitating their detection in HS-GC. By modifying the physical properties of the analytes, DMSO helps in achieving better separation and sensitivity during the chromatographic analysis.

Features and Benefits

Saturation Concentration in Air: 8.0 g/m3 (20 °C)

Analysis Note

Purity (GC): ≥ 99.8 %
Identity (IR): conforms
Evaporation residue: ≤ 3.0 mg/l
Water: ≤ 0.05 %
Color: ≤ 10 Hazen
GC/HS (Every residual solvent of class 1acc. ICH): ≤ 1 µg/g
GC/HS (Every residual solvent of class 2acc. ICH): ≤ 10 µg/g
GC/HS (Every residual solvent of class 3acc. ICH): ≤ 50 µg/g
Suitable as solvent for the analysis of residual solvents of ICH classes 1,2 and 3 according to Ph Eur and USP.
Formic acid, acetic acid, dimethylacetamide and cumene are not detected.

Other Notes

Explore various lab safety accessories and equipment for safe handling of solvents to increase your safety level from the first usage.

Legal Information

SUPRASOLV is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Supercools easily and remelts slowly at room temperature. Solidified product can be re-liquified by warming to room temperature without detriment to the product.

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Storage Class

10 - Combustible liquids

flash_point_f

188.6 °F - closed cup

flash_point_c

87 °C - closed cup

Certificates of Analysis (COA)

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Global Trade Item Number

SKU	GTIN
1019002500	04027269159269